What would be the effect of each type of the following mutations? a,) Mutation that destroys...
Homework Answers
A. DNA polmerase 
is responsible for initiation of DNA replication at the origin of
replication. So if any mutation occurs which leads to destruction
of the function of DNA plymerase
will not initiate the DNA replication process
B. DNA polymerase 1 mutation will lead to disruption of the following functions-
a. A 5'-3'(forward)DNA dependent DNA plymerase activity.
b. A 3'-5'(reverse) exonuclease activity (proofreading)
c. A 5'-3'(foward) exonuclease activity during DNA repair (nick translation)
d. A 5'-3' (forward) RNA dependent DNA polymerase activity.
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What would be the effect of each type of the following mutations?
a,) Mutation that destroys...
Temperature sensitive mutations are used to analyze biochemical pathways. A variety of mutations affecting DNA replication...
Temperature sensitive mutations are used to analyze biochemical pathways. A variety of mutations affecting DNA replication have been isolated in E. coli. What would you predict to see in the DNA after a mutation in each of the following occurred? (Answer each letter separately) (a) DNA ligase (b) DNA polymerase I (c) DNA polymerase III (d) Primase (e) Initiator Protein
The following DNA molecule is replicating and is going to undergo proofreading. To this end (in...
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Use the DNA sequence 3' CCCCATCAGTCAAGGGAA 5' to demonstrate the effect of each type of mutation...
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Match the following kinds of mutations with their characteristics or means of correction . Each item...
Match the following kinds of mutations with their
characteristics or means of correction . Each item is used only
once.
DNA mismatch during DNA replication
ultraviolet induced pyrimidine dimers
double stranded DNA breaks
apurinic sites single
base pair deletion
silent mutation
missense mutation
synonymous mutation
Match the following kinds of mutations with their characteristics or means of correction. Each item is used only once. DNA mismatch during DNA replication [Choose] [Choose) ultraviolet induced pyrimidine dimers does not change function of...
NA primase is TRUE? 27. Which ONE of the following statements about DNA primase is in...
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Describe DNA replication on the leading and lagging strands of DNA. Your answer must include a...
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1)Repairing damaged DNA is essential to maintaining the integrity of the genome. One type of repair...
1)Repairing damaged DNA is essential to maintaining the integrity of the genome. One type of repair is known as nucleotide excision repair. In this system, which order do the necessary enzymes act? A) exonuclease, DNA polymerase III, RNA primase B) helicase, DNA polymerase I, DNA ligase C) DNA ligase, nuclease, helicase D) DNA polymerase I, DNA polymerase III, DNA ligase E) endonuclease, DNA polymerase II, DNA ligase 2) What might be the result if all cells had functioning telomerase? A)...
4. The enzyme DNA polymerase has two important activities: 5-10-3 polymerase and 3 '-10-5'exonuclease. The 5'-to-3'...
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Which aspect of the E. coli DNA replication machinery accounts for high processivity? a. The beta...
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Describe the structure, Identify the different mechanisms of mutation and discuss the effect of these mutations...
Describe the structure, Identify the different mechanisms of mutation and discuss the effect of these mutations on survival. components, and function of DNA/RNA. . Identify importance of understanding teratogenic effects. . Differentiate between genotype and phenotype. Give examples of each. Identify major chromosomal abnormalities/aberrations. Differentiate between autosomal dominant, autosomal recessive, and X linked recessive inheritance modes. . Be able to interpret info provided for determining probability for these inheritance modes Describe sex-linked traits and give an example. .
Match the following kinds of mutations with their
characteristics or means of correction . Each item is used only
once.
DNA mismatch during DNA replication
ultraviolet induced pyrimidine dimers
double stranded DNA breaks
apurinic sites single
base pair deletion
silent mutation
missense mutation
synonymous mutation
Match the following kinds of mutations with their characteristics or means of correction. Each item is used only once. DNA mismatch during DNA replication [Choose] [Choose) ultraviolet induced pyrimidine dimers does not change function of...
NA primase is TRUE? 27. Which ONE of the following statements about DNA primase is in polymerase cannot extend a new A) It is necessary for DNA synthesis because DNA polymerase canno strand in the 3 to 5' direction. B) It proofreads bases added by DNA polymerase. C) It is a type of RNA polymerase. D) It has terminal transferase activity. 28. How many of the following statements about PCNA are TRUE? • It encircles ssDNA. • It is an...
4. The enzyme DNA polymerase has two important activities: 5-10-3 polymerase and 3 '-10-5'exonuclease. The 5'-to-3' polymerase makes one misincorporation per 100,000 incorporations. A misincorporation occurs when the "wrong" nucleotide-residue is added to the growing DNA-molecule, such that the added residue is NOT complementary in the normal Watson-Crick way (G with C, A with T) to the residue in the template DNA. Normally, the 3'-to-5'exonuclease corrects most of these misincorporations, reducing the misincorporation rate to one in 10,000,000. If a...
Describe the structure, Identify the different mechanisms of mutation and discuss the effect of these mutations on survival. components, and function of DNA/RNA. . Identify importance of understanding teratogenic effects. . Differentiate between genotype and phenotype. Give examples of each. Identify major chromosomal abnormalities/aberrations. Differentiate between autosomal dominant, autosomal recessive, and X linked recessive inheritance modes. . Be able to interpret info provided for determining probability for these inheritance modes Describe sex-linked traits and give an example. .
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