Question

2. Complete the following table by describing which stage of coll development the indicated factor is expressed and what function or role the factor plays in Boll development Factor. ILR Developmental stage Rag 1/2 complex nucleotides BAFF receptor Receptor editing mig CD19

I have a good idea of how to answer theae questions, but im wondering if they want specifics. This is from immunology

Answer 1

IL7R: Functions as Pre - Pro - B cell growth stimulating factor. Also plays an essential role in lymphoid cell survival.

TdT: Catalyzes the incorporation of single deoxynucleotides into the 3'-OH terminus of single or double stranded DNA.

Artemis: Plays an essential role in V(D)J recombination, the process by which B cell antibody genes and T cell receptor genes are assembled from V (variable), D(diversity) and J (joining) segments.

Lambda 5: Expresses speciafically in immature B- lineage cells. They express normal levels of VpreB m-RNA.