Question

4 Questions below are all connected to each other. PLEASE answer all of them so I can understand...

1. Make up a transmembrane segment sequence (by using one letter amino acid code) of a protein.

-> ITLIYFGVMAGVIGTILLIS <= This is what I made. Is this correct transmembrane segment sequence?

2. Make an amino acid sequence (by using one letter amino acid code) that bind to Bi. <= For this question, you just need to make own amino acid sequence

3. Why would you expect that BiP would not bind to sequence (your made up amino acid sequence from Q2) under “normal circumstances” in cell.

4. Give an example of a situation where BiP would be expected to bind your made-up protein (your made up amino acid sequence from Q2) in cell.

Answer 1

(Q: nu: 1). Transmembrane pooteins are integral proobin which helps damagandi of materials across the cell membrane At hydoophobic region contain high foacter of peopolor around acid and at Shycophilie region containing high frockers of polars amino acids 90 Queshon noi inital amincerids are non pobe grosseisuda a Dolaco 2) Both sides of integral protein should contain ood amino acids because these regions are badlaprilie middle amino acids are non polars Chrypraphobic :) >STCNGYSLIMAGYSNCOINYL Substance is hydrophobi will not be u integral protein Fa:hun) wintegral poradens binds with hydrophilie ers dansulez CamScanner