Question

6. Jasmine is a woman who is effected with a disease caused by a mutation in an imprinted gene that is paternally-expressed (maternally silenced). Jasmine and her male partner are considering having a child. Imagine you are a genetic counseler. Do you tell them they should worry about their child having the disease or not? Why? (2points) Jasmine's father is considering having a child with her new female partner (not Anurak's mother). Imagine you are a genetic counseler. Do you tell them they should worry about their child having the disease or not? Why? (2points) Jasmine remembers hearing that one of her parents' grandfathers had the same disease, but he can't remember which parent. Do you think it was his mother's grandmother or his father's grandmother? (1points) Is it surprising that Jasmine has the disease, given that she is a female? Why? (2points)

Answer 1

There is nothing to worry. Jasmine is affected by a disease which which is on a imprinted gene and also paternally expressed. It is maternally silenced. So there is nothing to worry .

Yes there is a chance for the disease. Because the mutation is paternally expressed.

It will be Father s grandparents

Jasmine is diseases because mutation has occurred in imprinted gene .