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In this activity you will explore yet another mode of inheritance which is a variation of...

In this activity you will explore yet another mode of inheritance which is a variation of classical Mendelism.

Cross two heterozygous long-legged flies.

F1 Observed Results:

900 long-legged flies

450 short-legged flies

Part 1: Which variation of leg length is dominant? Which is recessive? Why?

Part 2: What is surprising about the resulting phenotypic ratio?

Part 3: Suggest a hypothesis to explain these results.

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Answer #1

The given phenomenon is an example of 'Recessive homozygous lethality'
The given phenotypic ratio represents a 2:1 ratio.

Parental cross: Ll X Ll
Progeny: LL Ll Ll ll

LL = Long legs
Ll = Short legs
ll = Recessive homozygous lethality

Phenotypic ratio = 2:1

Dominant phenotype = Long legs
Dominant allele = L
Recessive homozygous phenotype = lethality
Recessive allele = l

The surprising thing about the phenotypic ratio is that a typical monohybrid cross should exhibit a 3:1 phenotypic ratio. However, the given phenotypic ratio = 2:1

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