Homework Answers
a.
Hemophilia is a sex linked recessive disorder or an X-linked inheritance. Due to the absene of clotting factor , the blood cannot clot properly. The X chromosome for normal person is XH for a Hemophilia person is Xh.
Hemophilia male - Xhy
Carrier female - XHXh
(It is said female parent is phenotypially normal and the daughter hemophiliac, so the female said to be carrier)
| XH | Xh | |
|
Xh |
XH Xh Female Normal carrier |
Xh Xh Female hemophiliac |
|
Y |
XHY Male normal |
XhY Male hemophiliac |
b.
Hemophilia is a X-linked disorder and there is only one X in the male. So presence of a single hemophilia Xhchromosome give 100 percentage chance of being hemophiliac. Where as the female has two X chromosome, the presene of a single hemophiliac chromosome XHXh make it a carrier only. The presence of XHXH only make the female hemophilia. So the chance of male becoming hemophiliac is more compared to females, but they can at as carrier.
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