The allele that causes sickle-cell anemia is the result of __________. a. two chromosomal translocations followed...
The allele that causes sickle-cell anemia is the result of __________.
a. two chromosomal translocations followed by fusions
b. an insertion leading to a frameshift mutation that changed all downstream codons
c. a single base substitution causing a transversion mutation
d. a silent mutation, which is why it goes unnoticed until adulthood
Homework Answers
The allele that causes sickle-cell anemia is the result of --
c. a single base substitution causing a transversion mutation.
Explanation - sickle-cell anemia is caused due changes a single base substitution of the beta-globin gene known as sickle hemoglobin (Hb S). Here mistakenly Valine is coded instead of glutamic acid, so here U-uracil(pyrimidine) is coded instead of A- adenine (purine) thus causing a transversion mutation.
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The allele that causes sickle-cell anemia is the result of
__________.
a. two chromosomal translocations followed...
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Sickle Cell Anemia Sickle cell anemia is the result of a type of mutation in the gene that codes for part of the hemoglobin molecule. Recall that hemoglobin carries oxygen in your red blood cells. The mutation causes these red blood cells to become stiff & sickle-shaped when they release their oxygen. The sickled cells tend to get stuck in blood vessels, causing pain and increased risk of stroke, blindness, damage to the heart & lungs, and other conditions. Analyze...
A mutation in one of the hemoglobin genes causes sickle cell anemia. The sickle cell allele, S, severely reduces fitness in people who are homozygotes, SS. In contrast, people with at least one normal hemoglobin allele, A, do not suffer the effects of sickle cell anemia, even if the individual is a heterozygote, AS. Interestingly, though, in areas with a high rate of malaria, heterozygotes that carry the sickle cell allele have a higher fitness than do individuals that are...
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