Question

1.)You have discovered two different compounds that seem to arrest the cell cycle at different stages. You treat plates of cells with both of your drugs, stain their DNA, and compare them to the control using flow cytometry.

Control Drug A Drug B Control (replicating cells) 100 50 DNA Content DNA Content DNA Content

1A.)Given your results, which of the drugs halts cells in G1? In G2?

1B.)Which drug more closely mimics what would occur if you treated control cells with a strong mitogen?

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