Homework Answers
26. Option B is correct. MHC-II binds to bacteria to allow macrophages to engulf the bacteria.
Explanation: MHC-II when binds to bacteria , it engulfs the bacteria by phagocytosis and process it to be presented. MHC-I cannot engulf bacteria by phagocytosis.
27. Option A is correct or true. it required protein digestion by the proteasome.
Explanation: In the first step the intracellular antigen is attached to a regulatory protein called ubiquitin by the enzyme ubiquitin ligase. Then this ubiquitin tagged protein is directed to proteasome for digestion and proteasome breaks it into 7-8 amino acid long peptide fragments.
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16. We said that MHC2 is mainly for presentation of exogenous antigens, whereas MHC1 is mainly...
Handout IG2-3 class Ma601 MH-Pepide Interactions place the steps of the antigen-processing pathway for exogenous antigens...
Handout IG2-3 class Ma601 MH-Pepide Interactions place the steps of the antigen-processing pathway for exogenous antigens in the correet CLIP fragment is exchanged for antigenic peptide. Invariant chain is degraded, leaving CLIP fragment Class II MHC peptide complex binds to CD4 T cell. Class II MHC antigenic peptide is transported to cell surface. Class II MHC binds invariant chain to block binding of endogenous anti MHC complex goes through Golgi complex. Exogenous antigen is taken in and degraded and routed...
The transporter in antigen processing genes encode subunits of a heterodimer pump that transports peptides from...
The transporter in antigen processing genes encode subunits of a heterodimer pump that transports peptides from the cytosol into the endoplasmic reticulum, where they can associate with newly translated Class la chains O B-2 microglobulin. Proteosomes. Immunoglobulin molecules. Class Il a and B chains. Question 20 5 pts Soluble proteins are examples of: Bone marrow dependent antigens. Bone marrow independent antigens., Thymus dependent antigens. Thymus independent antigens. Good food. The features of bound peptide fragments isolated from different class molecules...
12. Antimicrobials may a. produce allergic reactions b. produce toxic effects not only to the microbe...
12. Antimicrobials may a. produce allergic reactions b. produce toxic effects not only to the microbe but to the hoat c. kill bacteria in our bodies all the above 13. All of the following pertain to the role ofactivated helper T cells in cellular mediatesd immunity except a. differentiation into memory Th cells b. recognize MHC with antigenic peptide on macrophages c. activate Te cells indirectly lead to cytolysis through complement e. indirectl y lead to phagocytosis of large microorganisms...
Multiple Choice Questions 1. The natural, nonspecific resistance of the body to foreign invaders. First line...
Multiple Choice Questions 1. The natural, nonspecific resistance of the body to foreign invaders. First line of defense a. Innate immunity b. Adaptive immunity c. Component immunity d. High immunity 2. How do T cell help the body's immune system? a. Kill by contact b. Synthesize antibodies c. Immobilize antigens via contacting their immunoglobins d. None of the above 3. Adaptive immunity is also called_____________. a. Acquired immunity b. Advanced immunity c. Learned immunity d. Subjective immunity 4. Match the...
Multiple Choice Questions 1. The natural, nonspecific resistance of the body to foreign invaders. First line...
Multiple Choice Questions 1. The natural, nonspecific resistance of the body to foreign invaders. First line of defense a. Innate immunity b. Adaptive immunity c. Component immunity d. High immunity 2. How do T cell help the body's immune system? a. Kill by contact b. Synthesize antibodies c. Immobilize antigens via contacting their immunoglobins d. None of the above 3. Adaptive immunity is also called_____________. a. Acquired immunity b. Advanced immunity c. Learned immunity d. Subjective immunity 4. Match the...
35. Both humoral and cellular immunity share the following attributes except a. distinguishes self from non-self...
35. Both humoral and cellular immunity share the following attributes except a. distinguishes self from non-self b specificity mory first-line of defense e. involve the T-cell antigen pathway 36. Which of the following is common to viruses and antibodies? a. they are cell specific b. they can be cytolytic c. they can be phagocytic d. they contain lysozyme e. they contain nucleic acids 37. What non-specific immune component is directly responsible for the lysis of invading microorganisms? chemotaxis b. membrane...
please answer questions 20-27 Costcell and antigen presenting cell interaction is A MHC clase-It restricted CMHC...
please answer questions 20-27
Costcell and antigen presenting cell interaction is A MHC clase-It restricted CMHC class I restricted B MHC class-It restricted D. T-suppressor restricted 21. Which of the following are professional antigen presenting cells? A. Langerhans cells Chasophils B T-suppressors D. epithelial cells 22. T-cell dependent antigens can trigger a response from B-cells without the cooperation with macrophages or T-helper cells. A True B. False 23. Erythroblastosis fetalis develops in which of the following situations? A.fourth pregnancy Rh+...
ANSWER ALL QUESTIONS FULLY AND CORRECTLY 5-1 T cells recognize antigen when the antigen a. forms...
ANSWER ALL QUESTIONS FULLY AND CORRECTLY
5-1 T cells recognize antigen when the antigen a. forms a complex with membrane-bound MHC molecules on another host-derived cell b. is internalized by T cells via phagocytosis and subsequently binds to T-cell receptors in the endoplasmic reticulum c. is presented on the surface of a B cell on membrane-bound immunoglobulins d. forms a complex with membrane-bound MHC molecules on the T cell e. bears epitopes derived from proteins, carbohydrates, and lipids. 5-2 a....
AnswerB only which I marked Sample 4: Primary antibody: W6/32 (MHC class 1) Secondary antibody: rabbit...
AnswerB
only which I marked
Sample 4: Primary antibody: W6/32 (MHC class 1) Secondary antibody: rabbit anti-mouse FITC Condition: 4°C Please note: this image shows six cells at a smal scale than sample 3 Sample 3: Primary antibody: W6/32 (MHC class 1) Secondary antibody: rabbit anti-mouse FITC Condition: 22°C Please note: this image shows one single cell that has been enlarged Table 1 Experimental conditions and antibodies. Experimental conditions Primary antibody staining Secondary antibody staining Secondary Secondary antibody antibody type...
11. Which of the following complement pathways are activated by recognizing microbial products? a. Alternative and...
11. Which of the following complement pathways are activated by recognizing microbial products? a. Alternative and classical b. Lectin and classical c. Lectin and alternative d. All pathways; lectin, classical and alternative 12. True or False: Pathogen recognition receptors (PRR) recognize pathogen-associated molecular patterns (PAMP). a. True b. False 13. Which of the following is NOT true about the interferon response? a. Activates innate immune cells b. Increases the expression of MHC class I and antigen presentation by APCs c....
Handout IG2-3 class Ma601 MH-Pepide Interactions place the steps of the antigen-processing pathway for exogenous antigens in the correet CLIP fragment is exchanged for antigenic peptide. Invariant chain is degraded, leaving CLIP fragment Class II MHC peptide complex binds to CD4 T cell. Class II MHC antigenic peptide is transported to cell surface. Class II MHC binds invariant chain to block binding of endogenous anti MHC complex goes through Golgi complex. Exogenous antigen is taken in and degraded and routed...
The transporter in antigen processing genes encode subunits of a heterodimer pump that transports peptides from the cytosol into the endoplasmic reticulum, where they can associate with newly translated Class la chains O B-2 microglobulin. Proteosomes. Immunoglobulin molecules. Class Il a and B chains. Question 20 5 pts Soluble proteins are examples of: Bone marrow dependent antigens. Bone marrow independent antigens., Thymus dependent antigens. Thymus independent antigens. Good food. The features of bound peptide fragments isolated from different class molecules...
12. Antimicrobials may a. produce allergic reactions b. produce toxic effects not only to the microbe but to the hoat c. kill bacteria in our bodies all the above 13. All of the following pertain to the role ofactivated helper T cells in cellular mediatesd immunity except a. differentiation into memory Th cells b. recognize MHC with antigenic peptide on macrophages c. activate Te cells indirectly lead to cytolysis through complement e. indirectl y lead to phagocytosis of large microorganisms...
35. Both humoral and cellular immunity share the following attributes except a. distinguishes self from non-self b specificity mory first-line of defense e. involve the T-cell antigen pathway 36. Which of the following is common to viruses and antibodies? a. they are cell specific b. they can be cytolytic c. they can be phagocytic d. they contain lysozyme e. they contain nucleic acids 37. What non-specific immune component is directly responsible for the lysis of invading microorganisms? chemotaxis b. membrane...
please answer questions 20-27
Costcell and antigen presenting cell interaction is A MHC clase-It restricted CMHC class I restricted B MHC class-It restricted D. T-suppressor restricted 21. Which of the following are professional antigen presenting cells? A. Langerhans cells Chasophils B T-suppressors D. epithelial cells 22. T-cell dependent antigens can trigger a response from B-cells without the cooperation with macrophages or T-helper cells. A True B. False 23. Erythroblastosis fetalis develops in which of the following situations? A.fourth pregnancy Rh+...
ANSWER ALL QUESTIONS FULLY AND CORRECTLY
5-1 T cells recognize antigen when the antigen a. forms a complex with membrane-bound MHC molecules on another host-derived cell b. is internalized by T cells via phagocytosis and subsequently binds to T-cell receptors in the endoplasmic reticulum c. is presented on the surface of a B cell on membrane-bound immunoglobulins d. forms a complex with membrane-bound MHC molecules on the T cell e. bears epitopes derived from proteins, carbohydrates, and lipids. 5-2 a....
AnswerB
only which I marked
Sample 4: Primary antibody: W6/32 (MHC class 1) Secondary antibody: rabbit anti-mouse FITC Condition: 4°C Please note: this image shows six cells at a smal scale than sample 3 Sample 3: Primary antibody: W6/32 (MHC class 1) Secondary antibody: rabbit anti-mouse FITC Condition: 22°C Please note: this image shows one single cell that has been enlarged Table 1 Experimental conditions and antibodies. Experimental conditions Primary antibody staining Secondary antibody staining Secondary Secondary antibody antibody type...
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