In each section below, write the correct pKa values under the appropriate structure. pKa 1.25 4.74...
For each of the acid-base reactions in Section, compare the pKa values of the acids on either side of the equilibrium arrows and convince yourself that the position of equilibrium is in the direction indicated. (The pka values you need can be found in Section 2.3 or in Problem.) Problem: a. Which is a stronger base, CH3COO-or HCOO-? (The pKa of CH3COOH is 4.8; the p£a of HCOOH is 3.8.) b. Which is a stronger base, HO- or-NH2? (The pka...
OH pka 3.1 pKa 4.5 HO -OH pka 5.8 depicts the structure of citric acid with the corresponding pka values for each of the three acids. a. Explain why the carboxylic acid at the top of the structure is the most acidic. b. Suggest a reason why the remaining two acids would have different pka values.
What is the correct structure of histidine at pH 1? The pKa values are 1.8 (carboxylic acid), 9.2 (amine (conjugate acid)), and 6.0 (sidechain, the double bonded N in ring)?
What is the correct structure of histidine at pH 1? The pKa values are 1.8 (carboxylic acid), 9.2 (amine (conjugate acid)), and 6.0 (sidechain, the double bonded N in ring)? 0C NH H2 CH C NH, NH H2 CH-C NHS OH O=C NH A
Look up the pKa for water and acetone and write these values in the boxes below each molecule in the provided reaction scheme. Considering this information, which of the three reaction arrows best describes enolate formation? Considering the direction of the equilibrium from question 4, what do you think is the driving force for the aldol condensation?
Given below is the structure of Pregabalin. Write the structures of the predominant species of this drug at pH values1, 7.2, and 13. In each case your structure must clearly indicate the correct ionixation states of various ionizable functional groups in Pregabalin. 01; when Δ change in ion Some useful pKa values to remember H3N H OH pKa ds and sol lled the he Pregabalin tion. If reactant 10.4 xothery are weal ndother s is con 4.7 ed in solvat...
What is the correct structure of cysteine at pH 137 The pKa values are 1.7 (carboxylic acid), 10.8 (amine (conjugate acid)), and 8.3 (sidechain, thiol). ΝΗ, * _dp OH ΝΗ, HS H2 -CÁCH NH2 CH es O Arrange the indicated protons by acidity, most acidic first: So ho į III IV OI>I> III > IV 01>II> III > IV 01> IV> III > II >I> IV > III Friedel-Crafts alkylation reactions cannot be performed on aniline because: The amino group...
Interactive Case Study # 2 Henderson Hasselbach Relationship Can you help me find the correct pKa for each compound, and explain which one is the right answer? (d) Gaba, an important neurotransmitter in the human brain, is represented in different ionization states below. Circle the most dominant form of this compound at pH-7. Show work to justify how you arrived at this answer. To help, a generic pKa table has been provided on the next page but these values can...
Identify the glucose derivatives below by selecting the correct structure for each. Identify the glucose derivatives below by selecting the correct structure for each.
Write the correspondent protein structure for each protein structure below rite the correspondent protein structure for each protein structure below. Amino Acids leated sheet Alpha hek Pleated sheet Alpha alrite the condensation reaction for following two amino acids (ma