The insulin receptor is an example of a:
A. |
GPCR. |
|
B. |
JAK-STAT receptor. |
|
C. |
receptor tyrosine kinase. |
|
D. |
All of the above. |
|
E. |
A and B. |
Tha answer is C. Insulin receptor is alarge class of tyrosine kinase recptor. Janus kinase (JAK-STAT) is a cytokine receptor.
The insulin receptor is an example of a: A. GPCR. B. JAK-STAT receptor. C. receptor tyrosine...
Match the abbreviation with its full name. GPCR A. Mitogen-activated protein kinases RTK B. Non-receptor tyrosine kinase v NRTK C. G-protein coupling receptor MAPK D. Receptor tyrosine kinase
Insulin signalling acts through an insulin receptor, which is a receptor tyrosine kinase (TRUE OR FALSE?)
Explain the difference between amplification of signal by a tyrosine receptor kinase and a GPCR. Explain what would happen if you increased expression of a phosphatase or phosphodiesterase in each situation respectively.
You have developed an activator of a non-receptor tyrosine kinase. In three different cell types that all contain this receptor your drug has different effects. In cell type A you see activation of gene X and gene Y; in cell type B you note activation of Gene X, but no change in the mRNA levels for Gene Y. In cell type C your drug has no effect on either Gene X or Y. Describe how could each choice (A-D) be...
You have developed an activator of a non-receptor tyrosine kinase. In three different cell types that all contain this receptor your drug mas different effects. In cell type A you see activation of gene X and gene Y; in cell type B you note activation of Gene X, but no change in the mRNA levels for Gene Y. In cell type C your drug has no effect on either Gene X or Y. Describe how could each choice (A-D) be...
Which of the following signaling molecule function via JAK kinase and transcriptional regulatory protein STAT? Group of answer choices a. Ethylene oxide b. Prolactin c. TGF β d. EGF e. All of the above
Insulin binds to a receptor that_ I. is coupled to a G protein II. possesses tyrosine kinase activity III. possesses serine/threonine phosphatase activity IV. interacts with proteins such as IRS-1 I, IV I, III II, IV Oll only I, II, III
You perform an assay on the activity of the JAK tyrosine kinase using a 40 microliter aliquot of a lysate prepared from cells labeled for six minutes with radioactive cysteine. the total volume of the lysate is 5 milliliters (ml). In the aliquot, you measure the amount of all proteins and determine the presence of 13 micrograms of protein in 75 microliters of lysate. which of the following is the best calculation of the specific activity of the kinase in...
helppp Section: 12.3 GPCRS in Vision, Olfaction, and Gustation Section 12.4 21) Receptor tyrosine kinases: are dimers. e. f. do not regulate gene expression. g. engage in extensive cross talk with other signal transduction systems. h. bind insulin. Section: 12.4 Receptor Tyrosine Kinases Section 12.5 22) Protein kinase G: is activated by GMP. e. is a tyrosine kinase. is stimulated by sildenafil (Viagra). f. g. activates ion pumps in cardiac tiss h. Section: 12.5 Receptor Guanylyl Cyclases, CGMP, and Protein...
chapter 13 signal transduction molecules b) water molecules c) sodium ions d) ATP molecules oten, potdssium lohs are bonded to: a) glucose e to move potassium ions through a potassium ion channel is provided by: a electrostatic attraction between potassium ions and water molecules b) electrostatic attraction between potassium ions and carbonyl oxygens in the channel protein c) electrostatic repulsion between potassium ions d) ATP hydrolysis Chapter 13 Signal Transduction In this chapter we studied in detail 5 examples of...