Question

Someone answered 3'OH, Ribonucleotide, Triphosphate and Ribonucleotide respectively, but one is incorrect, I dont know which one. Please help.

The nucleotide shown here is called cordycepin triphosphate. It is a natural product of a fungus that is used in traditional medicines. P-P-P 5' Base он If cordycepin triphosphate is added to a cell-free transcription reaction, the nucleotide is added onto the growing RNA chain but then no more nucleotides can be added. Examine the structure of cordycepin and explain why it ends transcription Match the terms in the left column to the appropriate blanks in the sentences on the right. Terms can be used once, more than once, or not at all. Reset Help start codon 5'-phosphate Examination of the structure of cordycepin reveals that it lacks the This functional group is critical for addition of to the growing RNA chain, so after cordycepin is incorporated as a ribonucleoside into the RNA chain, it prevents the further addition monophosphate ribonucleotides stop codon triphosphate 3' OH

Answer 1

Examination of the structure of corydepcin revels that it lacks the 3’-OH. This functional group is critical for addition of ribonucleotides to the growing RNA chain, so after corydepcin is incorporated as a ribonucleoside monophosphate Into the RNA chain, it prevents further addition of ribonucleotides.