Question

Each monomer of the Lac repressor homotetramer has four domains: tetramerization, core, hinge, and headpiece. Identify the properties that are associated with each domain. Tetramerization Core Hinge Headpiece Answer Bank helix-turn-helix motif is an important component repressor dimer stabilized by association of this domain's two large hydrophobic clusters forces a 40° bend in DNA binds inducer binds to the minor groove of DNA binds to the major groove of DNA provides the only significant area of contact between all four monomers found at the C-terminal end of the repressor monomer

Answer 1

Answer:

Lac repressor domains

TETRAMERIZATION	CORE	HINGE	HEADPIECE
Found at the C terminal end of the repressor monomer.	Binds inducer	forces a 40 degree bend in DNA	Helix turn helix motif is an important component.
Provides the only significant area of contact between all four monomers.	Repressor dimer stabilized by this domain's two large hydrophobic clusters.	Binds to the minor groove of DNA	Binds to the the major groove of DNA