Question

Describe the infection cycle of the human immunodeficiency virus (HIV).

biochem

Answer 1

1-the viral enter the host , and by selective tropism on cd4 molceule receptor the viruses attack the T cell. , the virus is then internalized by surafce marker g120 of virion combine with cd4 receptor . , the later virus get uncoated and viral dna formation occur, once the birion has wntered the t cell cytoplasm reverse transcriptase of virus form single stranded dna , using single stranded dna as template. The viral intergeation occur , the viral dna get integrated with host cell but later viral integrase protein insert the viral dna into nuclues of host t cell. The viral replication occur the hiv provirus having become part og host cell dna the host cell dna transcriptase for viral rna witg presence of tat gene multiplicataion of viral particle lead to immune response and immune attack on host cell , thus the cd4 cell are destructed and viral disseminated.