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why weaning CHO cells off DMEN medium onto CD CHO medium important

why weaning CHO cells off DMEN medium onto CD CHO medium important

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CHO cells became popular because they have a low chromosome number and were used to study genetics.These characteristics have made CHO cells the most important cell line for the production of therapeutic proteins including humanized antibodies.Since the first use of CHO cells for recombinant protein expression, production processes have steadily improved through advances in cell line development ,clone screening and isolation,and optimization of basal media and feed supplements, as well as enhanced process monitoring and control.

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