Question

10.) Tatuo Aida investigated the genetic basis of color variation in the Medaka (Aplocheilus latipes), a small fish that occurs naturally in Japan (T. Aida. 1921. Genetics 6:554 573). Aida found that genes at two loci (B, b and R, r) determine the color of the fish: Fish with a dominant allele at both loci (B_R_ are brown, fish with a dominant allele at the B locus only (B_rr) are blue, fish with a dominant allele at the R locus only (bb R_) are red, and fish with recessive alleles at both loci (bb rr) are white. Aida crossed a homozygous brown fish with a homozygous white fish. He then bac ccrossed the F1 with the homozygous white parent and obtained 230 brown fish, 220 blue fish, 280 red fish, and 270 white fish. a) Write out the phenotypes and co responding genotypes of the individuals crossed in the described backcross and their progeny.

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Answer #1

Parental cross: Homozygous brown (BBRR) X Homozygous white (bb rr)
F1 progeny: BbRr
F1 backcross: BbRr X bbrr
Gametes: BR Br bR br X br
Progeny: BbRr Bbrr bbRr bbrr

F2 phenotypic ratio = 1:1:1:1
F2 genotypic ratio = 1:1:1:1

1 = Brown (B_R_) = BbRr
1 = Blue (B_rr) = Bbrr
1 = Red (bb R_) = bbRr
1 = White (bbrr) = bbrr

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