Question

Michael has excessively high blood level of ketone bodies, whereas Dave does not. Select all the reasonable explanations for Michael's excessive production of ketone bodies. O Michael's brain produces ketone bodies, which provides energy for his liver. Michael produces large amounts of ketone bodies because he has been severely hypoglycemic for most of the pas few weeks. Michael forms ketone bodies from the products of B-oxidation of fatty acids from stored triacylglycerides and the ingested fish oil. Michael forms ketone bodies from ketogenic amino acids released by protein catabolism.

Answer 1

So the correct options regarding this question are 2,3,4.

1.As the ketone bodies can be utilised by brain,heart but not the liver. Despite of being able to produce ketone bodies the liver itself can't utilise it for energy due to the lack of enzyme thiophorase. Option 1st is incorrect.

2nd option is correct because large amount of ketone bodies are formed when a person starves,low intake of food for a long time, carbohydrate restrictive diets which all results in a low blood sugar level(hypoglycemia),in order to which the body searches for other sources for the production of energy.

3rd option is also correct as the ketone bodies are synthesized by acetyl coA generated by beta oxidation of fatty acids in the liver mobilised from adipose tissue.Adipose tissue stores triacylglycerides.Also the ingested fish oil also produces ketone bodies.

4th option is correct as the protein catabolism breaks the protein into amino acids and simple derevative compounds.these simple amino acids can be highly ketogenic like leucine and lysine.