Question

Because the genetic code is nonoverlapping, a missense mutation (from a single nucleotide change) results in...

Because the genetic code is nonoverlapping, a missense mutation (from a single nucleotide change) results in the alteration of ______________­­, and the resulting protein has ______________.

a) only one codon / at least three amino acid changes

b) three codons / a single amino acid change

c) only one codon / a single amino acid change

d) three codons / three amino acid changes

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Answer #1

c) only one codon / a single amino acid change

Because the genetic code is nonoverlapping, a missense mutation (from a single nucleotide change) results in the alteration of only one codon and the resulting protein have a single amino acid change.

For example, TAC CCC GGG

mRNA- AUG GGG CCC

pROTEIN - MET - GLY- PRO

After mutation TAC CGC GGG

m RNA- AUG CGC CCC

PROTEIN - MET ARG PRO

So in this example, we see that a single nucleotide in DNA i.e4th nucleotide has been changed from C to G and it caused the change in one codon and one amino acid i.e it should have coded for glycine but after mutation, it codes for arginine.

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