Question

2. (3 pts) Does the GC polymorphism in the TAS2R38 gene cause an amino acid change (see page 182 where it shows taster and nontaster allele sequences-the GC mismatch is at base one of the codon)? So, is this GC polymorphism in the TAS2R38 gene considered a synomymous or non-synonymous mutation? What effect does the SNP have on the function of bitter taste perception?

Answer 1

The GC polymorphism in the TAS2R38 gene causes amino acid change. Therefore, it is considered as a non synonymous mutation. This mutation may affect the ability of the individual to perceive or not to perceive bitter taste.