Question

d. What is the probability that Alice's daughter, Lady May Albel Smith, was a carrier? Show your work. (2 pts) 6. Consider Prince Leopold's pedigree again. Pedigrees are often used to deduce the type of inheritance pattern, whether dominant, recessive, X-linked, etc. That is, it is evi- dent that hemophila is X-linked by noting who has the condition and who is a carrier. Explain how this information indicates that hemophila is an X-linked trait. (2 pts)

Answer 1

Answer. A) Genotype of Leopold is X^h Y (where X^h is recessive allele of hemophilia and X^H is dominant)

Answer d) genotype of Alice is X^H X^h while her husband genotype is X^H Y

So punnett square

	X^H	X^h
X^H	X^H X^H	X^H X^h
Y	X^H Y	X^H Y

The chance of Lady may albel Smith is1/4.

Answer 6. Leopold has disease while both male and female offspring are normal, but when Alice had son he had hemophilia. So its an X linked recessive condition. In this case affected Leopold transfer its X to Alice and Alice to son.