Homework Answers
Answer
1. Hormone transport & binding
2. Receptor conformational change
3. Translocation of hormone receptor complex
4. Transcription
5. Gene expression
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Place the stage of intracellular receptor signaling in the correct sequence of events.
Place each of the following events into the correct stage of cell signaling -A G protein...
Place each of the following events into the correct stage of cell signaling -A G protein catalyzes the hydrolysis of GTP to GDP and Pi -Receptor kinase dimerizes after binding insulin -Inactivation of a receptor kinase by a protein phosphatase -Changes in gene expression -Adrenaline binds the extracellular domain of a G protein-coupled receptor -Activation of protein kinase A (PKA)
Place the following events in Receptor Tyrosine Kinase signaling in order from the point when the...
Place the following events in Receptor Tyrosine Kinase signaling in order from the point when the RTK binds it ligand. A.) An SH2 domain proteins is recruited to phosphotyrosine residues B.) cytoplasmic tails of the RTKs cross-phosphorylate C.) RAS-GEF catalyzes GTP exchange on RAS D.) Receptors dimerize in the plasma membrane
Place the following events in the action of a hormone into the correct sequence. Hormone binds...
Place the following events in the action of a hormone into the correct sequence. Hormone binds to receptor in brain Endocrine gland releases hormone Genes control hormone production Organism changes behavior
Place the events in the correct sequence to explain signal transduction Molecular messenger transmits signal to...
Place the events in the correct sequence to explain signal transduction Molecular messenger transmits signal to effector proteins. Plant cell exposed to increased gibberellins. Effector proteins influence gene expression. Receptor molecule senses stimuli. The proteins produced influence cell division and elongation. Receptor molecule is converted to activated form. Receptor molecule senses stimuli.
une sequence of events involved in the cAMP second messenger system: a) Ligand binding to receptor...
une sequence of events involved in the cAMP second messenger system: a) Ligand binding to receptor > activate G protein > activate phospholipase C> increase intracellular CAMP > activate protein kinase A > phosphorylate proteins Ob) Ligand binding to receptor > activate G protein > activate phospholipase C> increase intracellular CAMP> activate protein kinase C > phosphorylate proteins c) Ligand binding to receptor > activate G protein > activate Adenylate cyclase > increase intracellular CAMP > activate protein kinase A...
Place in the right order the sequence of biochemical events that after the release of insulin...
Place in the right order the sequence of biochemical events that after the release of insulin into the bloodstream from the pancreas leads to the translocation of GLUT4 from internal vesicles to the plasma membrane of hepatocytes. (1) Insulin is released by the beta cells of the pancreas ( ) Binding of PKB to PIP3 promotes phosphorylation of PKB by PDK1 ( ) The catalytic site of the insulin receptor phosphorylates tyrosine residues of target intracellular proteins, among which the...
Explain using simple details and correspoding "ON" "OFF" signals. Describe signaling through the G-protein linked receptor....
Explain using simple details and correspoding "ON" "OFF" signals. Describe signaling through the G-protein linked receptor. Be sure to include the details of the receptor the associating G protein and its subunits, and the events in the sequence they occur. Be sure to include the reset for every step that is activated. Describe the signaling pathway that involves cAMP and G proteins. Include how each step is rest. Include dephosphorylation events. Assume involvement of PKA
How is signaling from receptor tyrosine kinases terminated? GTP hydrolysis ATP hydrolysis receptor endocytosis Arrestins Pathway...
How is signaling from receptor tyrosine kinases terminated? GTP hydrolysis ATP hydrolysis receptor endocytosis Arrestins Pathway crosstalk occurs when: signaling pathways use a common intermediate o signaling pathways split to produce multiple outcomes one signaling pathway triggers another signaling pathways produce the same outcome Eicosanoid hormones such as prostaglandins and leukotrienes are responsible for localized immune reactions such as to insect bites and hayfever symptoms. Which of the following best describes this level of cell signaling? Autocrine Endocrine o Holoerine...
Question 5 (2 points) Which is the most appropriate sequence of events in B cell signaling?...
Question 5 (2 points) Which is the most appropriate sequence of events in B cell signaling? Question 5 options: A) Antigen binds BCR, intracellular receptor kinases (such as Fyn, Lyn or Blk) are activated, Syk is recruited to ITAMs on Igα/Igβ. B) Antigen binds BCR, Syk is recruited to ITAMs on Igα/Igβ. intracellular receptor kinases (such as Fyn, Lyn or Blk ) are activated, C) Syk becomes activated, the BCR can now bind an antigen, and intracellular kinases are activated....
Growth factor signaling through receptor tyrosine kinases (RTKs) results in multiple phenotypic changes. These changes are...
Growth factor signaling through receptor tyrosine kinases (RTKs) results in multiple phenotypic changes. These changes are elicited in part by RTK activation of distinct yet specific intracellular signaling pathways. Describe the mechanism whereby a growth factor leads to the activation of several different yet specific pathways, and how that specificity is achieved. Begin with the growth factor and end with activation of the different intracellular signaling pathways. You must be comprehensive in your answer. Answer in no more than six...
Place the following events in the action of a hormone into the correct sequence. Hormone binds to receptor in brain Endocrine gland releases hormone Genes control hormone production Organism changes behavior
Place the events in the correct sequence to explain signal transduction Molecular messenger transmits signal to effector proteins. Plant cell exposed to increased gibberellins. Effector proteins influence gene expression. Receptor molecule senses stimuli. The proteins produced influence cell division and elongation. Receptor molecule is converted to activated form. Receptor molecule senses stimuli.
une sequence of events involved in the cAMP second messenger system: a) Ligand binding to receptor > activate G protein > activate phospholipase C> increase intracellular CAMP > activate protein kinase A > phosphorylate proteins Ob) Ligand binding to receptor > activate G protein > activate phospholipase C> increase intracellular CAMP> activate protein kinase C > phosphorylate proteins c) Ligand binding to receptor > activate G protein > activate Adenylate cyclase > increase intracellular CAMP > activate protein kinase A...
How is signaling from receptor tyrosine kinases terminated? GTP hydrolysis ATP hydrolysis receptor endocytosis Arrestins Pathway crosstalk occurs when: signaling pathways use a common intermediate o signaling pathways split to produce multiple outcomes one signaling pathway triggers another signaling pathways produce the same outcome Eicosanoid hormones such as prostaglandins and leukotrienes are responsible for localized immune reactions such as to insect bites and hayfever symptoms. Which of the following best describes this level of cell signaling? Autocrine Endocrine o Holoerine...
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