Homework Answers
ans (1.1)
~ There are two alleles of ADH1A gene segregating in the family. Individuals whose electropherograms exhibit two bands are heterozygous, whereas the individuals whose electropherograms exhibit with single band are homozygous.
ans (1.2)
~ Only the 3rd child is the recombination between the ADH1A and the boneitis- causing locus.
~ As the 1st, 4th , 5th ,6th, and 7th are the children with boneitis , whereas the 2nd and 8th are the children of ADH1A gene segregating
ans (1.3)
ans (1.5 )
(d) this analysis does not tell us anything about the molecular cause of boneitis.
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Dr. Zoidberg investigates the genetics causes of boneitis, a (fictional) bone disease for which the symptoms...
The autosomal dominant disease nail-patella syndrome is linked to the ABO blood type locus. The pedigree...
The autosomal dominant disease
nail-patella syndrome is linked to the ABO blood type locus. The
pedigree below shows a family in which some individuals are
affected by nail-patella syndrome. The blood type of each
individual is given as capital letters above each individual
symbol.
Can you explain this pattern without a cross-over event? If not
in which individual did the cross-over occur?
А. B — 1 2 АВ 0 ІІ 1 2 A B B B A B B A...
The autosomal dominant disease nail-patella syndrome is linked to the ABO blood type locus. The pedigree...
The autosomal dominant disease nail-patella syndrome is linked to the ABO blood type locus. The pedigree below shows a family in which some individuals are affected by nail-patella syndrome. The blood type of each individual is given as capital letters above each individual symbol. The image can also be downloaded here: Figure B Final.pdf A B - 2 AB II 2 A B B B A B B A 2 3 4 5 6 7 8 Can you explain this...
. O . Using Pedigrees to hypothesize patterns of inheritance 5. For each of the pedigree...
. O . Using Pedigrees to hypothesize patterns of inheritance 5. For each of the pedigree charts on the following page, determine which pattern of inheritance most likely explains the observed pattern of traits in the family shown. Observe the general patterns in the pedigree charts on the following page o males vs females? parents with disease? Compare these patterns with the clues on the previous page to hypothesize a pattern of inheritance Based on this pattern of inheritance, use...
Part B Determining genotypes in pedigrees of X-linked conditions The pedigree from Part A is shown...
Part B Determining genotypes in pedigrees of X-linked
conditions
The pedigree from Part A is shown below. Fill in the most likely
genotypes of the indicated individuals in the pedigree. Note that a
dominant allele followed by an underscore (_) indicates that either
the dominant or the recessive allele may be present at the second
position. Drag one pink label (for condition A, autosomal
recessive) to each pink target. Drag one blue label (for condition
B, X-linked recessive) to each...
BIO 340 Activity # 3: Trihybrid crosses, probability, and pedigrees (PAGE 1 of 2) Name (Last,...
BIO 340 Activity # 3: Trihybrid crosses, probability, and pedigrees (PAGE 1 of 2) Name (Last, First): 1. In garden pea plants, purple flowers (P) are dominant to white flowers (p), and full pod shape (F) is dominant to constricted pod shape (f). If two heterozygous plants (PpFf) are crossed, what are the potential genotypes and phenotypes that can be expected in the offspring? What is the genotype of the parents? х — What are the gametes for each parent?...
Styles 6. Insert a picture of your pedigree chart for this family with genotypes filled in...
Styles 6. Insert a picture of your pedigree chart for this family with genotypes filled in here. 7. Which pattern of inheritance do you think the disease shows? Explain your reasoning. 8. Patient 1 and Patient 2 in the pedigree chart would like to know what the chances are that they will have a child with the disease. What do you tell them? Use a Punnett Square to show your work. Using Punnett Squares for human conditions and diseases The...
Look carefully at the pedigrees below and: 1) indicate whether the transmission appears autosomal or sex-linked...
Look carefully at the pedigrees below and:
1) indicate whether the transmission appears autosomal or
sex-linked
2) indicate whether the transmission appears dominant or
recessive
3) provide at least two characteristics for each that support
your conclusion.
In general, the following characteristics suggest (but do not prove) specific inheritance patterns: Autosomal recessive inheritance: -affected individuals can be born to unaffected parents -if both parents are affected, all children are affected -observable effect of relatedness (consanguinity) -horizontal" inheritance: trait appears at...
Creating a pedigree chart from a family history and hypothesizing pattern of inheritance A family with...
Creating a pedigree chart from a family history and hypothesizing pattern of inheritance A family with a new disease caused by a mutant gene has been found. The family history has been collected and recorded. You will now create a pedigree chart from their family history and use the pedigree to predict the pattern of inheritance the disease follows. • Read the following family history: Patient 1 and Patient 2 visited a genetics counselor and provided their family histories. As...
Creating a pedigree chart from a family history and hypothesizing pattern of inheritance A family with...
Creating a pedigree chart from a family history and hypothesizing pattern of inheritance A family with a new disease caused by a mutant gene has been found. The family history has been collected and recorded. You will now create a pedigree chart from their family history and use the pedigree to predict the pattern of inheritance the disease follows. • Read the following family history: Patient 1 and Patient 2 visited a genetics counselor and provided their family histories. As...
In general, the following characteristics suggest (but do not prove) specific inheritance patterns: Autosomal recessive inheritance:...
In general, the following characteristics suggest (but do not prove) specific inheritance patterns: Autosomal recessive inheritance: -affected individuals can be born to unaffected parents -if both parents are affected, all children are affected -observable effect of relatedness (consanguinity) -horizontal" inheritance: trait appears at once among several members of one generation (siblings) *** Autosomal dominant inheritance each affected individual has an affected parent -when one parent is affected, transmission to the offspring (on average) *** -two unaffected parents do not transmit...
The autosomal dominant disease
nail-patella syndrome is linked to the ABO blood type locus. The
pedigree below shows a family in which some individuals are
affected by nail-patella syndrome. The blood type of each
individual is given as capital letters above each individual
symbol.
Can you explain this pattern without a cross-over event? If not
in which individual did the cross-over occur?
А. B — 1 2 АВ 0 ІІ 1 2 A B B B A B B A...
The autosomal dominant disease nail-patella syndrome is linked to the ABO blood type locus. The pedigree below shows a family in which some individuals are affected by nail-patella syndrome. The blood type of each individual is given as capital letters above each individual symbol. The image can also be downloaded here: Figure B Final.pdf A B - 2 AB II 2 A B B B A B B A 2 3 4 5 6 7 8 Can you explain this...
. O . Using Pedigrees to hypothesize patterns of inheritance 5. For each of the pedigree charts on the following page, determine which pattern of inheritance most likely explains the observed pattern of traits in the family shown. Observe the general patterns in the pedigree charts on the following page o males vs females? parents with disease? Compare these patterns with the clues on the previous page to hypothesize a pattern of inheritance Based on this pattern of inheritance, use...
Part B Determining genotypes in pedigrees of X-linked
conditions
The pedigree from Part A is shown below. Fill in the most likely
genotypes of the indicated individuals in the pedigree. Note that a
dominant allele followed by an underscore (_) indicates that either
the dominant or the recessive allele may be present at the second
position. Drag one pink label (for condition A, autosomal
recessive) to each pink target. Drag one blue label (for condition
B, X-linked recessive) to each...
BIO 340 Activity # 3: Trihybrid crosses, probability, and pedigrees (PAGE 1 of 2) Name (Last, First): 1. In garden pea plants, purple flowers (P) are dominant to white flowers (p), and full pod shape (F) is dominant to constricted pod shape (f). If two heterozygous plants (PpFf) are crossed, what are the potential genotypes and phenotypes that can be expected in the offspring? What is the genotype of the parents? х — What are the gametes for each parent?...
Styles 6. Insert a picture of your pedigree chart for this family with genotypes filled in here. 7. Which pattern of inheritance do you think the disease shows? Explain your reasoning. 8. Patient 1 and Patient 2 in the pedigree chart would like to know what the chances are that they will have a child with the disease. What do you tell them? Use a Punnett Square to show your work. Using Punnett Squares for human conditions and diseases The...
Look carefully at the pedigrees below and:
1) indicate whether the transmission appears autosomal or
sex-linked
2) indicate whether the transmission appears dominant or
recessive
3) provide at least two characteristics for each that support
your conclusion.
In general, the following characteristics suggest (but do not prove) specific inheritance patterns: Autosomal recessive inheritance: -affected individuals can be born to unaffected parents -if both parents are affected, all children are affected -observable effect of relatedness (consanguinity) -horizontal" inheritance: trait appears at...
Creating a pedigree chart from a family history and hypothesizing pattern of inheritance A family with a new disease caused by a mutant gene has been found. The family history has been collected and recorded. You will now create a pedigree chart from their family history and use the pedigree to predict the pattern of inheritance the disease follows. • Read the following family history: Patient 1 and Patient 2 visited a genetics counselor and provided their family histories. As...
Creating a pedigree chart from a family history and hypothesizing pattern of inheritance A family with a new disease caused by a mutant gene has been found. The family history has been collected and recorded. You will now create a pedigree chart from their family history and use the pedigree to predict the pattern of inheritance the disease follows. • Read the following family history: Patient 1 and Patient 2 visited a genetics counselor and provided their family histories. As...
In general, the following characteristics suggest (but do not prove) specific inheritance patterns: Autosomal recessive inheritance: -affected individuals can be born to unaffected parents -if both parents are affected, all children are affected -observable effect of relatedness (consanguinity) -horizontal" inheritance: trait appears at once among several members of one generation (siblings) *** Autosomal dominant inheritance each affected individual has an affected parent -when one parent is affected, transmission to the offspring (on average) *** -two unaffected parents do not transmit...
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