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What is the major difference between the mechanisms of homology-­directed repair, copy choice, and gene conversion...

What is the major difference between the mechanisms of homology-­directed repair, copy choice, and gene conversion in DNA repair?

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Homology directed repair (HDR) mechanism: The homologous recombination is the most common form of homology directed repair, which is used in the repair of double stranded lesions of DNA. The cell can use HDR mechanism only if it contains the homologous region of DNA, probably either in the G2 or S phase.

Copy-choice repair or copy-choice recombination mechanism: The new DNA molecule is formed by the replication of each selected parental DNA (or RNA) molecules (with alternative maternal and paternal copies).

Gene conversion is a mismatch repair mechanism in which one allele is replaced by another homologous allele (transfer is unidirectional from the donor to recipient), the allele may be of the same gene.

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