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In chloroplasts, glyceraldehyde 3-phosphate dehydrogenase uses NADPH as a cofactor in the synthesis of glucose. In...

In chloroplasts, glyceraldehyde 3-phosphate dehydrogenase uses NADPH as a cofactor in the synthesis of glucose. In cytoplasmic gluconeogenesis, however, the isozyme of this dehydrogenase uses NADH.

Why is it advantageous for the enzyme in the chloroplast to use NADPH? :

NADPH is abundant in chloroplasts, because it is generated by the light reactions.

NADPH provides more reducing power than NADH in cells.

NADPH is harmful to chloroplasts when levels become too high.

The presence of NADH increases the rate of wasteful photorespiration.

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