A newly discovered natural product shows a therapeutic effect against coronavirus. The product, as purified from cute puppies, has an optical rotation of aobs= -15.7° for a 20-cm sample containing 1500mg of a sample per liter. Your'e working on a synthetic version, so you don't have to use cute puppies to make. Useful info: aobs= [a] x C x l, Where C is g/dL and l is path length in dm. Thus, [a]= aobs/ (Cxl)
A) Convert the given concentrations and path length to the appropriate units for optical rotation.
B) From the measured sample, What is the specific rotation of the compound?
C) You made a synthetic sample with aobs= -19.1° for a 20mg/mL solution in a 2-dm cell. What was the enantiomeric excess (EE) of your sample?
D) The FDA standards for experimental drugs is that it can have no greater than 10% of the incorrect enantiomer if it is to be used for clinical trials. Was your synthesized sample good enough? Explain.
A newly discovered natural product shows a therapeutic effect against coronavirus. The product, as purified from...