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1. Proteins can have similar structure despite have different sequence. Explain why this is possible. Also,...

1. Proteins can have similar structure despite have different sequence. Explain why this is possible. Also, some protein may have conservative sequence. Explain the significance of this conservative sequence in proteins.

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Answer #1

Proteins have similar structure yet they have differ in amino acid composition in polypeptide because as we know that during secondary or tertiary structure formation there will be bonding such as hydrogen bonding, vanderwall bonding, disuplhide bridge occurs between amino acid.

If the interaction occurs in such a way that same shape is regained by means of such bonding in between amino acid, then they have same shape yet amino acid is different in two polypeptide.

Some protein have conservative sequence due to following reasons:

This conserved sequences provide proper folding in different protein.

This sequences also helps in substrate binding to active sitewhen proteins are of enzymatic nature.

In proteins, it provides structural stability to them.

*Such conserved sequences are found even in different species.

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