What type of cell death is most often induced in cancer cells by radiation and chemotherapy drugs? Why is this? (ie- which factor is often missing in cancer cells?)
Chemotherapy is used to kill the cancerous cells and reduce the tumors. It is used to destroy the cell division control center. Chemotherapy mainly targets the fast dividing cells and we know that the cancerous cells divide rapidly. So it leads to apoptosis of cancer cells.
The reasons behind uncontrolled growth of cancerous cells are-
-Lack of contact inhibition in which a cell stops to divide when come in contact with adjacent cells.
-Due to presence of telomerase enzyme.
- lack of tumor protein p53 which is required at checkpoint.
Thanks.
What type of cell death is most often induced in cancer cells by radiation and chemotherapy...
What characteristic makes cancer cells susceptible for radiation/chemotherapy?
Why might inhibition of LDH in cancer cells lead to cancer cell death? Explain why conjugating an LDH inhibitor to glucose leads to preferential targeting of cancer cells?
Customary treatment for metastatic cancer, chemotherapy and radiation, execute growth cells by inciting apoptosis. Be that as it may, disease cells get to be safe in view of numerous systems in particular, multidrug resistance pumps, temperamental genomes, changes, and so on. Propose elective medications that might be more fruitful against tumors and that don't include the apoptotic pathway (caspase-autonomous pathways). please include the page where you got it from.
Cancer cells often lack normal DNA damage response and cell-cycle control mechanisms. Why does this make them more susceptible to DNA-damaging chemotherapies? O Cancer cells will arrest in the cycle and will not grow further O Cancer cells with activating mutations in Ras will amplify the damage through the Ras signaling pathway Cancer cells might ignore the normal mechanisms that halt the cell cycle in response to damage, and subsequent division with damage leads to death, O Cancer cells have...
Chemotherapy targets fast growing cells in the body induding cancer cells and its side effects are caused by targeting non-cancer cells with a high mitotic rate. Which of the following tissue types would be most likely to be destroyed by chemotherapy because one of its key characteristics is a high regeneration rate? Oa. Dense regular connective tissue Ob. Simple columnar epithelium Oc. Cardiac muscle Od. Nervous tissue Oe. Hyaline cartilage QUESTION 2 Intercalated discs and striations suggest the presence of...
1. Compare the signs of fibrocystic disease and breast cancer. 2. Explain why chemotherapy and radiation may be recommended following surgery for breast cancer even when no lymph nodes appear to be involved. 3. Explain the recommended treatment for estrogen dependent breast cancer in premenopausal and postmenopausal women. 4. Explain what is meant by targeted therapy for breast cancer. 5. Discuss the importance of breast cancer screening and early diagnosis.
please help me with these quetions DNA replication is checked G1 for accuracy Cells no longer divide GO DNA is copied or replicated Cells synthesize proteins G1 needed for the process of mitosis Cell doing its normal 'job GO 30 Crossing over between non Meiosis sister chromosomes Spindle formation complete Prophase I Nuclear membrane reforms Metaphase Chromosomes line up at Metaphase midline Spindle fibers shorten Telophase 13. Cell |Туре Normal Mitotic Index C A E 3% 5% 8% 12% 15%...
cancer arises after many mutations occur in cell. which of the following cells are most likely to have increased mutations over time. a) cardiac muscle b) neurons c) blood
Depletion of cholesterol in the cell membrane using a drug (mevastatin) has been associated with apoptosis in cancer cells. a. What effect would cholesterol depletion have on the integrity of lipid rafts in the membrane? b. Researchers found that FAS death receptor was activated in cholesterol depleted cancer cells. Explain how activation of this receptor activates killer caspases. c. When a caspase is converted from its inactive to its active form there are changes in the primary and tertiary structure...
What type of radiation exposure monitoring device is used most often by Radiologic Technologist? How is this device different from others? In your own words, explain advantages and disadvantages.