One way mutations can affect the phenotype is by altering the coding sequence of a gene...
Homework Answers
1. if a mutation occurs in transcription level or regulates on this level, for example, a mutation in an activator or repressor protein that not a part of the protein-coding sequence can also regulate the expression of a particular gene and also phenotype.
2. Translocation if a small part of chromosome change location then due to position effect it can be highly express or may b not sufficient, so in this gross mutation gene of expression and phenotype can be change.
Add Answer to:
One
way mutations can affect the phenotype is by altering the coding
sequence of a gene...
8. (6) There are three common types of point mutations that can affect the coding sequence...
8. (6) There are three common types of point mutations that can affect the coding sequence of proteins. What are these mutations? How do the mutations change the mRNA sequence and consequently the protein? 9. (2) If you were to suggest gene therapy to the family, how you describe what the main goal of this therapy is? 10. (2) Different virus have been used as vectors for gene therapy. Andenoviruses are one example that have been used in humans. What...
Most nonsense mutations in a structural gene for a protein have a null phenotype. How many...
Most nonsense mutations in a structural gene for a protein have a null phenotype. How many different single base substitution mutations in a protein coding sequence can produce a nonsense mutation?
7. Open reading frames A protein coding gene includes the following sequence on one of its...
7. Open reading frames A protein coding gene includes the following sequence on one of its two DNA strands. Note that this segment (within an exon) does NOT include either the start codon or the stop codon for this gene. However, because five of the six potential reading frames (3 on each DNA strand) in this region include stops, only the true reading frame remains "open" through this segment. Therefore, it is possible to unambiguously decode (translate) this segment of...
The following sentences describe chromatin structure and how altering chromatin structure can affect gene expression. Complete...
The following sentences describe chromatin structure and how altering chromatin structure can affect gene expression. Complete each sentence using the words provided.In some cells, DNA combines with proteins to form a substance calledThe lowest level of chromatin structure consists of DNA wrapped twice around a group of histones to form a(n)The formation of nucleosomes may block the binding of transcription factors and RNA polymerase II to theThe structure of chromatin can be modified by altering either the DNA or the...
4. Imagine the following DNA sequence is a real sequence of a gene (coding strand). This...
4. Imagine the following DNA sequence is a real sequence of a gene (coding strand). This gene has only one exon meaning no sequence is spliced out during RNA processing. a) What will be the amino acid sequence this gene codes for? 15 points will be given for a completely correct amino acid sequence. You can get partial points if: the beginning of the amino acid sequence is correct (at least two first amino acids, 4 points), and/or the end...
QUESTION 7 Consider the hypothetical gene show here. The gene coding sequence consists of 4 exons...
QUESTION 7 Consider the hypothetical gene show here. The gene coding sequence consists of 4 exons (shown in solid colors). The 5' UTR and 3' UTR are shown as striped boxes. 25 150 200 300 400 25 Based on the lengths of the exons, you should be able to calculate a rough estimate of the protein encoded by this gene, assuming that all 4 exons are translated and the protein does not undergo any significant processing (cleavage or chemical modifications)....
3. Mutations in bacteria that affect gene regulation may have a cis- or trans-effect on the...
3. Mutations in bacteria that affect gene regulation may have a cis- or trans-effect on the expression of the protein-encoding genes in an operon? How would the following mutations affect the expression of the lac operon? Assume there could be more than one lac operon in the cell and that no glucose is present. A. A mutation in the operator site that prevents the lac repressor from binding. B. A mutation in the lacI gene that prevents allolactose from binding,...
Inheritance and Mutations in a Single-Gene Disorder (10pts - all questions worth 0.5pts) Some diseases are...
Inheritance and Mutations in a Single-Gene Disorder (10pts - all questions worth 0.5pts) Some diseases are caused by the environment. For example, exposure to chemicals or extremely bright lights can cause certain forms of blindness. But other forms of blindness are inherited, meaning that they are passed on from one generation to another. In this activity, you will learn about a young woman, Molly Troxel, who has an inherited form of blindness called Leber congenital amaurosis (LCA). The activity explores...
5. Consider the wild-type F8 gene. What would happen to the 1) transcript (mRNA) sequence and...
5. Consider the wild-type F8 gene. What would happen to the 1)
transcript
(mRNA) sequence and quantity, 2) to the protein (sequence,
quantity, function) and 3) the person’s
overall phenotype if they were homozygous (both copies of the
gene are the same) for a 3 base-pair
deletion in the:
i. First intron
ii. First exon
iii. The promoter
iv. 5’UTR
v. Last exon
6. What environmental factor could affect the phenotype caused
by an F8 null mutation?
Thrombophilia is a...
Background Information How can we predict where a coding gene will be in bacteria? And can...
Background Information How can we predict where a coding gene will be in bacteria? And can we then predict what protein will be produced? Take the DNA sequence below, for example. tcaggctttaattcatccgtgatctttgacgacggtaaatacgatgcagatataatacgatgaccgatgccaatcgaccgatcaaggaggcaccgaatggcgatgatggcgatgattgcgattaacgaagtggaacgcattatggcgggcattaacgaagatacccatgcgaccggcgaaaacgaaaccatttgcagctgcgcgaactttgaagaactgacccatgcgaccggccgcgaagcgacctaaaagtcgtaattacgtatcaagtcatgggccgcgggcgcccggcccactgactagactagggccgggcgcccgcggcccaccatataaataaaaaaaaaaaaaacgaggctatagctcatcaatgacct If you were a bacterial RNA polymerase, what sequence(s) should there be in this DNA for you to bind and begin transcribing? And if you found such sequence(s), where would you begin transcription? As a human being looking at this fragment of DNA, what type of consensus sequence(s)...
7. Open reading frames A protein coding gene includes the following sequence on one of its two DNA strands. Note that this segment (within an exon) does NOT include either the start codon or the stop codon for this gene. However, because five of the six potential reading frames (3 on each DNA strand) in this region include stops, only the true reading frame remains "open" through this segment. Therefore, it is possible to unambiguously decode (translate) this segment of...
The following sentences describe chromatin structure and how altering chromatin structure can affect gene expression. Complete each sentence using the words provided.In some cells, DNA combines with proteins to form a substance calledThe lowest level of chromatin structure consists of DNA wrapped twice around a group of histones to form a(n)The formation of nucleosomes may block the binding of transcription factors and RNA polymerase II to theThe structure of chromatin can be modified by altering either the DNA or the...
4. Imagine the following DNA sequence is a real sequence of a gene (coding strand). This gene has only one exon meaning no sequence is spliced out during RNA processing. a) What will be the amino acid sequence this gene codes for? 15 points will be given for a completely correct amino acid sequence. You can get partial points if: the beginning of the amino acid sequence is correct (at least two first amino acids, 4 points), and/or the end...
QUESTION 7 Consider the hypothetical gene show here. The gene coding sequence consists of 4 exons (shown in solid colors). The 5' UTR and 3' UTR are shown as striped boxes. 25 150 200 300 400 25 Based on the lengths of the exons, you should be able to calculate a rough estimate of the protein encoded by this gene, assuming that all 4 exons are translated and the protein does not undergo any significant processing (cleavage or chemical modifications)....
Inheritance and Mutations in a Single-Gene Disorder (10pts - all questions worth 0.5pts) Some diseases are caused by the environment. For example, exposure to chemicals or extremely bright lights can cause certain forms of blindness. But other forms of blindness are inherited, meaning that they are passed on from one generation to another. In this activity, you will learn about a young woman, Molly Troxel, who has an inherited form of blindness called Leber congenital amaurosis (LCA). The activity explores...
5. Consider the wild-type F8 gene. What would happen to the 1)
transcript
(mRNA) sequence and quantity, 2) to the protein (sequence,
quantity, function) and 3) the person’s
overall phenotype if they were homozygous (both copies of the
gene are the same) for a 3 base-pair
deletion in the:
i. First intron
ii. First exon
iii. The promoter
iv. 5’UTR
v. Last exon
6. What environmental factor could affect the phenotype caused
by an F8 null mutation?
Thrombophilia is a...
Most questions answered within 3 hours.
-
How do ECM Solutions assist in embedding a culture of continuous
improvement in an organization? (Project...
asked 11 minutes ago -
Directions
These directions introduce the idea of Essential Questions.
Since this may be a new concept...
asked 13 minutes ago -
1.b. Fiscal policy is said to suffer from ‘crowding out’.
Explain what this means and why...
asked 31 minutes ago -
The equation for the reaction of nitrogen and oxygen to form
nitrogen oxide is written as...
asked 35 minutes ago -
A scientist reproducing some photoelectric effect experiments
shines a light on a metal electrode, but doesn't...
asked 38 minutes ago -
In a study designed to test the effectiveness of magnets for
treating back pain, 35 patients...
asked 58 minutes ago -
Here are summary statistics for randomly selected weights of
newborn girls:
nequals=193,
x overbarxequals=30.5
hg,
sequals=7.3...
asked 47 minutes ago -
Exercise #3:
Create the “MathTest” class. It will have two class variables:
1) a question and...
asked 50 minutes ago -
In epidemiology, how do you calculate the overall incidence of
cure within two groups? What formula...
asked 54 minutes ago -
A 1 liter solution contains 0.357 M ammonium chloride and 0.268
M ammonia. Addition of 0.295...
asked 55 minutes ago -
What are the advantages and disadvantages of using virtual
reality simulations in health care education?
asked 1 hour ago -
Given input { 66, 28, 43, 29, 44, 69, 19 } and a hash function
h(x)...
asked 1 hour ago