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10. A mutation in the DNA that codes for a protein has caused an amino acid...

10. A mutation in the DNA that codes for a protein has caused an amino acid with a polar charged side chain to be replaced with one that has a polar uncharged side chain. What effect should this have?

More likely to be hydrophobic

More likely to form an ionic bond

More likely to form hydrogen bonds

More likely to form disulfide bridges

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Answer #1

Hydrophobic bond is formed between two hydrophobic residues. But in the given case polar charged side chain to be replaced with one that has a polar uncharged side chain. So option A is wrong.

Disulfide linkage is formed between two cysteine residues. So option D is also wrong.

An ionic bond is formed between an amino acid which has a positive charge side chain and amino acid which has a negative charge side chain. But in the given case polar charged side chain to be replaced with one that has a polar uncharged side chain. So option B is wrong.

An amino acid which a polar charged group can form a hydrogen bond with amino acid which has a polar side chain. in the given case polar charged side chain to be replaced with one that has a polar uncharged side chain. So the polar amino acid can form H-bond.

hence correct answer is option C. More likely to form hydrogen bonds

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