A is the normal allele at the Beta-globin locus, but in a malarial region of western...
A is the normal allele at the Beta-globin locus, but in a malarial region of western Africa, the S allele of this locus is present at a frequency of 0.2. SS individuals have sickel-cell anemia and have only a 10% chance of surviving to reproductive age relative to heterozygous individuals with the AS genotype. Normal individuals with the AA genotype at this locus have an 85% chance of surviving to reproductive age, relative to AS individuals. Assume that at this locus, the genotypes of newborns are in Hardy-Weinberg properties.
a)If the relative fitness of AS individuals is 1, what is the average viability in this population?
b) What are the genotype frequencies among individuals of reproductive age?
Homework Answers
Ans:
Relative Fitness (w) is the survival and/or reproductive rate of a genotype (or phenotype) relative to the maximum survival and/or reproductive rate of other genotypes in the population.
Calculate the Relative Fitness (w) of each genotype by dividing each genotype's survival and/or reproductive rate by the highest survival and/or reproductive rate among the 3 genotypes.
Survival rate = the overall survival rate is the % of individuals born that survive to reproductive age. But often we can only measure the % that survive over some period of time, e.g. the survival rate of fledglings, the survival rate from one year to the next, or the survival rate through a winter storm.
Reproductive rate = for any given genotype or phenotype, the average number offspring born per individual.
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A is the normal allele at the Beta-globin locus, but in
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