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What are the potential risks of a single large comprehensive experiment in contrast to a sequential...

  1. What are the potential risks of a single large comprehensive experiment in contrast to a sequential approach?
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A single large comprehensive experiment requires the complete knowledge of various factors of the experiment, the levels of each factor and their ranges, the methodology and unit of measurement of each factor and other details completely without any ambiguity before the start of the experiment.

Sequential approach consists of a series of related tests. The information gained at each stage of experimentation is considered to continue the investigation.

Thus, the potential risks of a single large comprehensive experiment in contrast to a sequential approach consist of the absence of possible improvement in the knowledge base in stages as in sequential approach. Sequential test is thus more effective than a single large comprehensive experiment.

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