Question

What effect did each drug have on cell motility? a. Cytochalasin D b. Cholchicine c. Taxol

What effect did each drug have on cell motility?

a. Cytochalasin D

b. Cholchicine

c. Taxol

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Answer #1

Name of drug

Effect

Cytochalasin D

It is reported to belong to the class of mycotoxins. Cytochalasin D is a potential inhibitor of actin polymerization and it is permeable through the cell. It is capable of disrupting the actin microfilaments. This drug is believed to bind to F-actin polymer and averts the polymerization of actin monomers.

Cholchicine

Colchicine interferes with the formation of microtubules by disrupting the polymerization of β-tubulin. The drug prevents the activation, degranulation, and motility of neutrophils to places of inflammation.

Taxol

Taxol disturbs the microtubule dynamics and can potentially suppress the plus-end dynamics of microtubules in the viable cells. It is also reported to inhibit the compaction of microtubules eventually inactivating it.

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