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Nicardipine HCl is administered in the short-term treatment of hypertension by slow IV infusion as a...

Nicardipine HCl is administered in the short-term treatment of hypertension by slow IV infusion as a 0.1 mg/mL solution. A 10 mL vial containing 25 mg of nicardipine should be added to what volume of D5W to make the desired concentration?

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Answer #1

0.1 mg nicardipine HCl is present in 1 ml solution

25 mg nicardipine HCl is present in 1×25/0.1 ml solution

= 250 ml solution.

Thus, volume of D5W should be 250-10 = 240 ml.

So that concentration become same.

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