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A mutant yeast strain is found with a mutation affecting some of its tRNA Tyr. The...

A mutant yeast strain is found with a mutation affecting some of its tRNA Tyr. The wild type normally produces a tRNA that recognizes the codon 5’ UAC 3’, and is charged with the amino acid Tyrosine (Tyr) (its notation is tRNATyr). The mutant tRNA is still charged with Tyr, but the anticodon is mutated and now has the sequence 5’- UUA3’. How will some of the proteins produced in these yeast cells be different from the wild type proteins?

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Answer #1

The tRNA that recognizes the codon 5’ UAC 3’ So anticodon is 5' GUA 3'

Mutated anticodon is 5' UUA 3'. So it actual codon is 5' UAA 3' it is a stop codon.

So, in the stop codon 5' UAA 3' this mutated tRNA binds and adds a Tyrosine and translation wont stop and elongation still take place. The mutated strain has long amino acid sequence compare to wild type.

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