32. Fill in the table
Exotoxin |
Cytotoxin, neurotoxin or enterotoxin |
Action on host |
hemolysin |
||
tetanus toxin |
||
cholera toxin |
||
C. difficile toxin |
||
leucocidin |
||
botulism toxin |
Exotoxins are bacterial toxins which are among the most lethal toxins in the world. They are thermolabile and soluble proteins generally released by gram-positive bacteria. However, it has been noted that some gram-negative bacteria is also capable of producing exotoxins.
The following table includes the nature and effects of some exotoxins given above.
Name of the exotoxin | nature of toxin | Effect on host |
Hemolysin | cytotoxic | it lyses erythrocytes of the host |
Tetanus toxin | neurotoxin | spastic paralysis |
Cholera toxin | enterotoxin | causes diarrhoea |
C.difficile toxin | enterotoxin | causes diarrhoea, abdominal pain and discomfort, fever etc. |
Leucocidin | cytotoxic | forms pores on leucocytes, cause degranulation of lysosomes within leukocytes resulting in the decrease of the host resistance. |
Botulinum toxin | neurotoxin | decrease in acetylcholine release. Causes flaccid paralysis. |
32. Fill in the table Exotoxin Cytotoxin, neurotoxin or enterotoxin Action on host hemolysin tetanus toxin...
QUESTION 2 A neurotoxin produced by a species of Clostridium, this type ill toxin binds to inhibitory interneurons of the spinal cord and blocks their release of inhibitor molecules. This causes spastic paralysis, a condition where opposing flexor and extensor muscles simultaneously contract. Death is usually from respiratory failure. A toxold can be used to immunize against this disease. Tetanus exotoxin Botulism exotoxin Streptococcal pyrogenic exotoxin (SPE) Shiga toxin Leukotoxin
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