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What do we call the phenomenon where the expression of one gene or two genes can...

What do we call the phenomenon where the expression of one gene or two genes can then affect the expression of another gene? Why is this concept so powerful in terms of genetic expression in multicellular organisms?

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The phenomenon where the expression of one gene or two genes can then affect the expression of another gene is called Epistasis.

This is important in terms of gene expression in multicellular organisms having signal transduction. Signal transduction is a series of events that involves the action of numerous proteins/biomolecules leading to the expression of a certain gene, if some gene encoding for a protein in the signal transduction is missing then the required gene cannot be transcribed.

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