Question

1Differentiate ischemic stroke and hemorrhagic stroke according to the following: etiology, diagnosis/clinical presentation, and treatment.

2 What role does glutamate play in neuronal injury during ischemia?

Answer 1

1) The difference between ischaemic stroke and hemorrhagic stroke is given below,

	Ischaemic stroke	Haemorrhagic stroke
Etiology	It occurs due to clotting of blood in the cerebral arteries	It occurs due to leakage if blood into the brain parenchyma due to high blood pressure
Diagnosis/clinical presentation	Progressive onset Intracranial tension is raised. CT scan shows dense homogenous area	Sudden onset Intracranial tension is normal. CT scan shows spotted areas.
Treatment	Fibrinolytic therapy	Control of blood pressure and seizures

2) Glutamate is an excitatory neurotransmitter and is involved in causing death of nerve cells in brain.