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What would be the consequence for impulse conduction if the Na+ channels were able to reopen...

What would be the consequence for impulse conduction if the Na+ channels were able to reopen immediately after they had closed during an action potential?

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Answer #1

Normally during the depolarization phase, Na+ channel opens, Na+ come inside and upstroke of action potential can be sensitive. When the membrane potential reaches +30mV , voltage senstive Na+ channel closed and K+ channel open leading to repolarization or down stroke of action potential.

Na+ channel undergo 3 state changes during this procedure. Resting stage---->Active stage-----> inactive stage----> Resting stage.

It take certain time to convert from Inactive stage to resting stage & in the inactive stage of Na+ channel,howev ho the strong stimulus it is , Na+ channel can't be open again ( absolute refractory period) . Once it reach resting stage ,it can be open again.

Now coming to the question, if Na+ channel open immediately after the closed, the absolute refractory period will decrease.

Secondly the downstroke of action potential will not be complete and in the mid-way of down stroke,it will again begin an upstroke.

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