Question

How does microbial control work in our bodies? How does it effect drug resistance?

Answer 1

There are several ways to control microbes in our body. There are some micro-organisms in our body that are beneficial for our body. The gram negative bacteria E. coli lives in our intestine and helps to supply vitamin B₁₂. There are several microorganisms that can harm our body by occurring several types of diseases. Our body has its own system to protect the body from the disease causing microbial attack. The system is known as immunity system. There are several cells such as macrophage, neutrophil etc can engulf the microorganisms and kill them. There are another mechanism to kill the intracellular microbes, known as cytotoxicity that kills the microorganism affected cells through apoptosis. There are some proteins in our immunity system, known as complement which kills the bacteria by lysis of the cell wall. So, by these mechanism the level of microbes can be controlled.

Drug resistance is the phenomenon where a drug remains inefficient to kill the microbe. If a drug is applied for long periods of time then the microbes can tolerate the drug. If we can stimulate the immunity power of our body then we don't need to apply any drug to kill the microorganisms. So, microorganisms don't get the scope to resist against any drug because the immune system of our body can kill the microbes efficiently.