Why do lac^-d alleles (one of mutations in lac repressor) have a dominant-negative affect? explain it...
Homework Answers
Lac repressor is composed of 4 subunit and active in its tetrameric form. If all the 4 repressor subunit are wild type only then repressor is able to bind at operator. If even one of the subunit is mutated the repressor is poisoned and is not able to bind to operator. Lac-D mutation is a dominant negative because the activity of wild type allele is reduced by product of mutated lac ID allele which are able to bind and form a tetramer but can't bind to operator.
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Why
do lac^-d alleles (one of mutations in lac repressor) have a
dominant-negative affect? explain it...
3. Mutations in bacteria that affect gene regulation may have a cis- or trans-effect on the...
3. Mutations in bacteria that affect gene regulation may have a cis- or trans-effect on the expression of the protein-encoding genes in an operon? How would the following mutations affect the expression of the lac operon? Assume there could be more than one lac operon in the cell and that no glucose is present. A. A mutation in the operator site that prevents the lac repressor from binding. B. A mutation in the lacI gene that prevents allolactose from binding,...
B2. Consider E. coli cells, each having one of the following mutations: a) a mutant lac...
B2. Consider E. coli cells, each having one of the following mutations: a) a mutant lac operator (Oc locus) that cannot bind repressor. b) a mutant lac repressor (I- gene product) that cannot bind to the lac operator. c) a mutant lac repressor (the Is gene product) that cannot bind to lactose. d) a mutant lac promoter that cannot bind CAP + cAMP. What effect would each mutation have on the function of lac operon (assuming no glucose is present)...
Can you explain how to do number 4? dominant individual and umail mmetance, hów can one...
Can you explain how to do number 4?
dominant individual and umail mmetance, hów can one differentiaté between a homozygous one who is heterozygous for the dominant trait? (A) By crossing the individuals in question (B) By crossing each individual with a known homozygous recessive and examining the offspring By crossing each individual with a known heterozygote and examining the offspring (C) (D Both B and C If a male hemophiliac (Xhy) is crossed with a female carrier of both...
Cor.. 38 wor D Question 10 2 p Do dominant alleles have a higher fitness (better...
Cor.. 38 wor D Question 10 2 p Do dominant alleles have a higher fitness (better survival rate) than recessive alleles? Why or why not?
7. Why do dominant alleles tend to be advantageous and recessive alleles tend to be disadvantageous...
7. Why do dominant alleles tend to be advantageous and recessive alleles tend to be disadvantageous in most populations? 8. You are studying a population of parrots and you observe that there are two alleles for wing color. Allele 1 codes for green wings and is dominant over allele 2, which codes for red wings. Allele 2 is at a frequency of 70% of the population, what should be the frequency of allele 1 homozygotes? 9. You are studying a...
Explain why recessive pathogenic mutations often segregate at higher frequencies than dominant pathogenic mutations in human...
Explain why recessive pathogenic mutations often segregate at higher frequencies than dominant pathogenic mutations in human populations. (3 points)
Question 2: Explain why recessive pathogenic mutations often segregate at higher frequencies than dominant pathogenic mutations...
Question 2: Explain why recessive pathogenic mutations often segregate at higher frequencies than dominant pathogenic mutations in human populations. (3 points)
Is it likely that most people will have one dominant image of change management? Why? Why...
Is it likely that most people will have one dominant image of change management? Why? Why not? Are change leaders more likely to be successful if they remain faithful to their dominant style(s)? Why? Why not? Are change leaders who have the capacity to apply a range of different images more likely to be successful? Why? Why not? In your judgment, do most managers have the behavioral flexibility to move between different styles, or do they tend to apply just...
17) Why are dominant lethal alleles difficult to pass on? What are three circumstances in which dominant lethal...
17) Why are dominant lethal alleles difficult to pass on? What are three circumstances in which dominant lethal alleles can be passed on to future generations? how do dominant lethals usually arise in a population if it is so difficult to pass them on? 18) What does it mean by male mammals being “hemizygous” for sex chromosomes? 19) Select the true statements about sex chromosomes and sex-linked genes. Circle all that apply. The Y chromosome only contains genes for “maleness”. In mammals, the father has no...
1. (1 pt) If a gene is repressible and under positive control, A. Is the regulatory...
1. (1 pt) If a gene is repressible and under positive control, A. Is the regulatory protein an activator or repressor? B. Explain how an effector molecule, which binds to the regulatory protein, alters the regulatory protein’s ability to regulate expression of the gene. 2. (1 pt) Cis and trans are two terms used to describe mutations. A. Explain the molecular difference between these terms. B. indicate which type of mutation (cis or trans) is dominant to wild-type and which...
Can you explain how to do number 4?
dominant individual and umail mmetance, hów can one differentiaté between a homozygous one who is heterozygous for the dominant trait? (A) By crossing the individuals in question (B) By crossing each individual with a known homozygous recessive and examining the offspring By crossing each individual with a known heterozygote and examining the offspring (C) (D Both B and C If a male hemophiliac (Xhy) is crossed with a female carrier of both...
Cor.. 38 wor D Question 10 2 p Do dominant alleles have a higher fitness (better survival rate) than recessive alleles? Why or why not?
Question 2: Explain why recessive pathogenic mutations often segregate at higher frequencies than dominant pathogenic mutations in human populations. (3 points)
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