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What is the difference between one-gene/one-protein hypothesis and one-gene/one-polypeptide hypothesis?

What is the difference between one-gene/one-protein hypothesis and one-gene/one-polypeptide hypothesis?

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One gene-one Protein hypothesis was first given by Archibald Garrod in 1909. It said that each gene codes a single, specific enzyme. Thus under this hypothesis, each gene is responsible for the enzyme initiating a single step in a metabolic process.

One gene-one Polypeptide hypothesis was first given by George Beadle in 1945. It said that each gene is responsible for the synthesis of a single polypeptide. This theory was modified because it was realized that genes also encoded nonenzyme proteins and individual polypeptide chains.

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