Question

1. Explain the difference between activation of g-protein coupled recepetor activation and direct gene activation. A....

1. Explain the difference between activation of g-protein coupled recepetor activation and direct gene activation.

A. Which one happens faster?
B. Which one lasts longer?
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Answer #1

Direct gene activation directly influences gene expression & is located within the nucleus, nuclear receptors bind directly to DNA to regulate genes expression whereas, in g-protein coupled receptor activation, activity is mediated & amplified within the cells bypass the action of second messenger mechanism

A) Direct gene activation is faster

B) Direct gene activation last longer as G protein coupled receptor activation depends on the concentration of hormone in the blood.

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