G-protein coupled receptors can exhibit which of the following actions? Select one: a. Dimerization b. Tyrosine...
G-protein coupled receptors can exhibit which of the following actions?
Select one: a. Dimerization b. Tyrosine kinase activity c. Nuclear Localization d. Activation of Adenylate Cyclase e. ATPase activity
Homework Answers
G-protein coupled receptors can exhibit which of the following actions?
Answer: (A) Dimerization.
G-protein-coupled receptors have classically been assumed and hypothesized to exist as monomers. However, recent studies revealed the existance of GPCR oligomer which is a protein complex that consists of a small number od GPCRs, held together by covalent bonds or by intermolecular forces. The subunit within this complex is called as protomers and the identical protomers together constitute receptor hormone called as "receptor homodimers". Receptor heterodimers consist of two different GPCRs which is the simplest heteromeric GPCR oligomers. The necessity of dimerization is explained by the metabotropic γ-aminobutyric acid b receptor (GbR), which is composed of two subunits GbR1 and GbR2 . Under monomeric condition, GbR1 is retained intracellularly and unfunctional GbR2 reaches the cell surface.
Add Answer to:
G-protein coupled receptors can exhibit which of the following
actions?
Select one: a. Dimerization b. Tyrosine...
A. B. C. D. E. F. Thank you receptors induce activation of adenlyate cyclase, which creates...
A. B. C. D. E. F. Thank you
receptors induce activation of adenlyate cyclase, which creates the second messenger(s) O G-Protein Coupled, CAMP O Tyrosine Kinase, CAMP OTyrosine Kinase, IP3 and DAG G-Protein Coupled, IP3 and DAG Which of the following is most likely to be activated by a small hydrophobic signal? OIntracellular receptor Receptor Tyrosine Kinase O G-Protein Coupled Receptor Ligand-Gated lon Channel Which of the following types of receptors require dimerization for activation? (Select any/all that apply) OLigand-gated...
Which one of the following statements is false? a. Many growth factor receptors are tyrosine kinases....
Which one of the following statements is false? a. Many growth factor receptors are tyrosine kinases. b. SH2 is an example of a protein domain that has high affinity binding for phosphorylated EGFR. c. Raf initiates a serine/threonine kinase cascade. d. Raf is activated by the kinase activity of RAS. Which one of the following statements is true? a. Retroviruses are a major cause of human cancers. b. Proto-oncogenes are altered forms of normal genes. c. Oncogenic activation of receptor...
Which type of receptors do steroid hormones generally employ? O G-protein coupled receptors O enzyme-coupled receptors...
Which type of receptors do steroid hormones generally employ? O G-protein coupled receptors O enzyme-coupled receptors nuclear receptors O ion-channel coupled receptors What type of cell response would take the longest amount of time (on the scale of minutes to hours) to execute? one that involves the release of secretory vesicles one that stimulate lamellipodia formation by regulating the actin cytoskeleton one that involves a change in gene expression one that uses a phosphorylation event to activate an enzyme
Which of the following events normally activates a receptor tyrosine kinase GTP hydrolysis by the protein...
Which of the following events normally activates a receptor tyrosine kinase GTP hydrolysis by the protein Dimerization and phosphorylation Activation of an upstream GTPase-activating protein Phosphorylation of a bound GDP molecule by an upstream phosphorylase
The following class of receptors either associates with a kinase or has a kinase domain: a....
The following class of receptors either associates with a kinase or has a kinase domain: a. enzyme coupled receptors b. G protein coupled receptor c. nuclear receptor d. ion channel coupled receptor
Choose all of the following that are differences between kinase receptors and G- protein linked receptors....
Choose all of the following that are differences between kinase receptors and G- protein linked receptors. a) Kinase receptors span the membrane one time while G-protein linked receptors span the membrane many times b) Kinase receptors phosphorylate other proteins while G-protein linked receptors do not c) There are no differences between Kinase and G-protein linked receptors d) G-protein linked receptors bind to steroids while kinase receptors do not e) G-protein linked receptors are are attached to a G protein while...
label the terms Cellular Action of Hormones a water-soluble hormone growth factor type hormone 0000000000 protein...
label the terms
Cellular Action of Hormones a water-soluble hormone growth factor type hormone 0000000000 protein kinase nucleus cellular response phosphorylated intracellular protein espons ular response Hormone Receptors and Signaling # 10 - 17 Complete the matching from the PDF file provided. a) Cyclic adenosine monophosphate 10) 11) Pg.145#1 Pg.145#2 12) 13) 14) 15) 16) 17) Pg. 145#3 Pg. 145#4 Pg. 145#5 v Pg.145#6 Pg.145#7 Pg. 145#8 b) Nuclear receptor c) Gene transcription d) Lipid-soluble hormone e) Tyrosine kinase f)...
INFORMATION ABOUT IMAGE G FOR QUESTIONS 12-15: GABAB receptors (GABABRs) are G-protein-coupled receptors that can be...
INFORMATION ABOUT IMAGE G FOR QUESTIONS 12-15:
GABAB receptors (GABABRs) are
G-protein-coupled receptors that can be found on both pre- and
postsynaptic neurons. When they are activated by GABA, they can
have a range of effects. For the synapse you are studying in the
following questions, the effects of GABABRs are
indicated in IMAGE G.
You are doing a series of experiments in which you are recording
from the pre- and postsynaptic cell at a synapse. The experiments
described below...
Protein kinase A phosphorylates _____, which then activates _____. A) phosphorylase kinase; glycogen phosphorylase B) protein...
Protein kinase A phosphorylates _____, which then activates _____. A) phosphorylase kinase; glycogen phosphorylase B) protein phosphatase 1; glycogen synthase C) glycogen phosphorylase; phosphoglucomutase D) adenylate cyclase; phosphorylase kinase
Some G-protein coupled receptors (GPCRs) are associated with a protein called RGS, which stimulates the GTPase...
Some G-protein coupled receptors (GPCRs) are associated with a protein called RGS, which stimulates the GTPase activity of the receptor’s G-protein. What effect does RGS have on GPCR signaling? a. Signaling events are activated (upregulated) due to an increase in cAMP levels. b. Signaling events are downregulated due to disruption of the receptor-ligand interaction. c. Signaling events are activated as PKA as inhibition from the regulatory subunits is abolished. d. Signaling events are downregulated as the G-protein adopts its inactive...
A. B. C. D. E. F. Thank you
receptors induce activation of adenlyate cyclase, which creates the second messenger(s) O G-Protein Coupled, CAMP O Tyrosine Kinase, CAMP OTyrosine Kinase, IP3 and DAG G-Protein Coupled, IP3 and DAG Which of the following is most likely to be activated by a small hydrophobic signal? OIntracellular receptor Receptor Tyrosine Kinase O G-Protein Coupled Receptor Ligand-Gated lon Channel Which of the following types of receptors require dimerization for activation? (Select any/all that apply) OLigand-gated...
Which type of receptors do steroid hormones generally employ? O G-protein coupled receptors O enzyme-coupled receptors nuclear receptors O ion-channel coupled receptors What type of cell response would take the longest amount of time (on the scale of minutes to hours) to execute? one that involves the release of secretory vesicles one that stimulate lamellipodia formation by regulating the actin cytoskeleton one that involves a change in gene expression one that uses a phosphorylation event to activate an enzyme
Choose all of the following that are differences between kinase receptors and G- protein linked receptors. a) Kinase receptors span the membrane one time while G-protein linked receptors span the membrane many times b) Kinase receptors phosphorylate other proteins while G-protein linked receptors do not c) There are no differences between Kinase and G-protein linked receptors d) G-protein linked receptors bind to steroids while kinase receptors do not e) G-protein linked receptors are are attached to a G protein while...
label the terms
Cellular Action of Hormones a water-soluble hormone growth factor type hormone 0000000000 protein kinase nucleus cellular response phosphorylated intracellular protein espons ular response Hormone Receptors and Signaling # 10 - 17 Complete the matching from the PDF file provided. a) Cyclic adenosine monophosphate 10) 11) Pg.145#1 Pg.145#2 12) 13) 14) 15) 16) 17) Pg. 145#3 Pg. 145#4 Pg. 145#5 v Pg.145#6 Pg.145#7 Pg. 145#8 b) Nuclear receptor c) Gene transcription d) Lipid-soluble hormone e) Tyrosine kinase f)...
INFORMATION ABOUT IMAGE G FOR QUESTIONS 12-15:
GABAB receptors (GABABRs) are
G-protein-coupled receptors that can be found on both pre- and
postsynaptic neurons. When they are activated by GABA, they can
have a range of effects. For the synapse you are studying in the
following questions, the effects of GABABRs are
indicated in IMAGE G.
You are doing a series of experiments in which you are recording
from the pre- and postsynaptic cell at a synapse. The experiments
described below...
Most questions answered within 3 hours.
-
could someone please post clear drawings of the three structures
in the equilibrium mixture of D-glucose...
asked 3 minutes ago -
Using the Properties of Order show that 5n5 +
4n4 + 6n3 + 2n2+ n +...
asked 6 minutes ago -
What is experiential learning and how is it helpful for teaching
leadership, and interpreting group dynamics?...
asked 6 minutes ago -
A security awareness policy defines the responsibilities of
managers and information owners.
True
False
asked 7 minutes ago -
which is the equilibrium expression for the reaction
3A(g)+4B(g)<---> 2C(g)+5D(g)
asked 8 minutes ago -
Create a balanced compensation plan that you feel would
encourage a restaurant manager to be more...
asked 16 minutes ago -
Re: Human Physiology
Comment on the differences between representing V02 max as an
absolute number and...
asked 18 minutes ago -
A firm with a WACC of 10% is considering the following mutually
exclusive projects:
0
1...
asked 23 minutes ago -
. A 100.0 mL sample of 0.18 M HClO4 is titrated with 0.27 M
LiOH. Determine...
asked 46 minutes ago -
A regression equation that describes the relationship between
the amount of the bill ($) at a...
asked 1 hour ago -
exercise on VSEPR and molecular structrue.
octahedral
SeCl62-
TeCl62-
ClF62-
distorted
SeF62–
IF6–
asked 2 hours ago -
284 mL of a 0.52 M potassium hydroxide solution is added to 467
mL of a...
asked 2 hours ago