Question

answer T/F : - chloride ion binds ONLY to deoxyHb -chloride ion forms a bridge between...

answer T/F :

- chloride ion binds ONLY to deoxyHb

-chloride ion forms a bridge between the two Beta chains of Hb

-Chloride ion exchanges with biocarbonate ions across ERTHROCYTE membrane

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Answer #1

1.chloride ion binds ONLY to deoxyHb
Answer True
This is bohr effect.
chloride ions bind more strongly to deoxyhemoglobin.

2.chloride ion forms a bridge between the two Beta chains of Hb
Answer False
bridge between the two Beta chains of Hb is generally a salt bridge.The epsilon-amino group of Lys-40 alpha forms a salt bridge with the alpha-carboxyl group of beta chain in deoxyhemoglobin.


3.Chloride ion exchanges with biocarbonate ions across ERTHROCYTE membrane
Answer True

This mechanism is called as chloride shift. It is the exchange of chloride and carbonate between the plasma and the erythrocytes.

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