1. - rate of mutation
s-selection coefficient for recessive allele ( frequency)
q^= stable equilibrium
q^ =/s
s= /q^
Frequency of allele changes with mutation rate.
2. Natural selection is based on fitness value. The fitness value for complete selection can be found by selection equation for complete dominance.
q = [pq] [(q)(W2 - W1) + (p)(W1 - W0)]
W = fitness phenotypes W0=homozygous dominant, W1= heterozygous & W2= homozygous recessive
Change of allele frequency - q
p and q= frequency of dominant and recessive allele.
In complete dominance the change of allele frequency is optimal. And in incomplete dominance, there will be an equilibrium frequency q^.
how does mutation rate affect the equilibrium value of the recessive allele ? how does complete...
1) What is the molecular basis of dominant and recessive alleles (for complete dominance; ignore incomplete dominance, epistasis, etc.)? To answer this question, consider the following: a) If alleles are copies of the same gene, why are two types of alleles? What differentiates a dominant allele from a recessive allele (at the molecular level)? Be specific (base pairs, transcription/translation method, protein produced, etc.) b) Why is the phenotype determined by the dominant allele in heterozygous genotype? Be specific. c) What...
If selection favours the dominant allele and mutation is creating recessive alleles at a rate of 0.006 per generation in balance with the rate at which selection is eliminating them, if the frequency of the recessive allele is 0.03 what is the rate of selection in this balanced state (round to the nearest 0.001)?
Question 1 Which of the following is NOT true regarding Hardy-Weinberg equilibrium (HWE)? Most real species will not be at HWE at all loci within their genome If a locus has genotype frequencies consistent with HWE, then the species as a whole is not evolving If a locus has genotype frequencies consistent with HWE, then no evolution is occurring at that locus If a locus does NOT have genotype frequencies consistent with HWE, then some form of evolution is occurring at that locus Question 2 Which of...
how does natural selection affect allele frequency over several generations?(hypothesis:))
For the four evolutionary processes below, indicate: how they affect allele and genotype frequencies within a population, whether or not these effects are random, and how they affect differentiation between populations. Number your answers as indicated in the table below to indicate which part of this question you are answering: Process Within-population allele & genotype frequencies Random?Y/N Genetic differences between populations #1 #9 Natural Selection Genetic Drift Mutation #6 #10 . #11 Migration between populations #4 #12
This is Population Genetics. 6.11. Calculate the equilibrium allele frequency (9-) for each of the following fitness sets. Assume 110° in each case. What is the effect of partial dominance on the mutation-selection equilibrium? Explain in biological terms. (hint: use dominance model for fitness, 1. l-hs, 1-5) WI 1 0 .95 10.90 0.9 0.9 0.98 0.99 098
3. In pea plants, T is the allele for tall plants, while t is the allele for dwarf plants. If you have a tall plant, demonstrate with a testcross how it could be determined if the plant is homozygous tall or heterozygous tall. 4. Explain how incomplete dominance is different from complete dominance, a example of incomplete dominance 3. In pea plants, T is the allele for tall plants, while t is the allele for dwarf plants. If you have...
What is the equilibrium frequency of a recessive gene arising with a mutation rate of 4×10−6 and a reproductive fitness in homozygotes of 0.8? What would it be if the gene were partially recessive with h = 0.05? How different are these two equilibrium frequencies? Explain the difference. Calculate and compare the genetic loads under these two conditions (use the full equation for ¯w).
This is Population Genetics. WI W IT 0.9 0.9 b 1 0 .95 0.90 e 1 0. 990 .98 6.15a Cystic fibrosis (CF) is a fatal disease caused by a recessive mutation. Individuals homozygous for the CF allele die before reproducing. The frequency of the CF allele is about 0.02 in some populations. Assume these populations are at equilibrium, and assume this CF allele is maintained in the population by mutation-selection equilibrium and the heterozygotes have no reduction in viability....
What is heterozygote superiority? In a two-allele system, how does heterozygote superiority affect allele frequencies? What are the evolutionary implications of this for recessive lethal alleles? Use Mukai and Burdick’s experiment to illustrate the above. (based off of ch6 and 7 of evolutionary analysis 5th edition)