Question

COVID 19 is a positive sense single stranded RNA virus. Which of the following is the case, given this information?

		It integrates its RNA into a host cell
		this group of viruses is not generally known to infect humans
		It requires viral reverse transcriptase to convert its genome into a positive sense RNA strand
		it has a double stranded genome
		the genome does not need to be transcribed in order for viral proteins to be produced

Answer 1

Answer-

According to the given question-

• COVID-19 belongs to group of Coronaviruses that are responsible for causing several disease such as upper respiratory tract disease as well as responsible for organ failure in humans.
• They have a positive-sense single-stranded RNA genome with the nucleocapsid which are of helical symmetry.
• positive-sense single-stranded RNA genome work as the messenger RNA and not need to be transcribed when enter into host cell and directly translated into protein.
• while Negative-sense viral RNA are complementary in structure with the messenger RNA and they changed by the enzyme RNA-dependent RNA polymerase into positive-sense RNA after that they are translated into protein inside the host cell.
• Due to this reason the positive-sense single-stranded RNA genome causes infection directly while negative-sense single-stranded RNA genome are not capable of causing infections.

So the correct answer for the question COVID-19 is a positive sense single stranded RNA virus (E) the genome does not need to be transcribed in order for viral proteins to be produced