Question

E. coli makes curli fibers on its cell surface that are bacterial amyloid proteins. These curli are used as models to study eukaryotic amyloid proteins in human disease such as Alzheimer's. In E. coli the protein used to secrete curli fibers is CsgG. Using NCBI, search for this protein - "csgG E. coli. K12 W3110" in the protein database, and select the RefSeq protein entry. From the right-hand side of the protein page, select 'Run BLAST'. Select 'Escherichia coli (taxid:562)' from the 'Choose Search Set: Organism' and check EXCLUDE and click BLAST to search CsgG sequence using default search parameters. Based on the search result which species of bacteria has the protein with the highest identity?

Leclercia adecarboxylata

Salmonella enterica

Shigella dysenteriae

Citrobacter koseri

Answer 1

Answer is Shigella dysenteriae