Question

(1) One of the standard techniques to determine whether two loci are physically close to one another on the same chromosome is to conduct a "dihybrid cross", a cross of two individuals that are heterozygous at both loci. For example if the two loci have alleles A and a at the first locus and B and b at the second locus then crossing two AaBb individuals (where the capital alleles are known to be on the same chromosome) is performed. If the loci are not close to one another or are on different chromosomes then the expected frequencies of the gametes would be 1/4 AB, 1/4 Ab, 1/4 aB and 1/4 ab-leading to expected frequencies of 1/16 for each of the possible gamete combinations in the offspring Consider the following situation. At the first locus AA homozygotes are Black while aa homozygotes are white and the A allele is dominant to the a allele. At the second locus BB individuals are large while bb individuals are small and Bb individuals are intermediate in size. An experiment is conducted in which two AaBb heterozygotes are crossed to produce a large number of offspring with phenotypes in the following numbers Black large Black intermediate Black small White large White intermediate While small Observed 293 691 276 123 235 103 Perform a chi-square test to determine whether the loci are likely to be physically close to one another (a, 4 pts) What X2 value do you obtain? (report to nearest 0.001) (b, 2 pts) How many degrees of freedom do you have for this X statistical test? df (c, 2 pts) State the technical conclusion of your X2 test in the box below. Use the grammar described in lecture and state with what degree of confidence you make your conclusion by providing the most specific range of p values from the table provided in lecture. You must use the phrase "significantly different" or "not significantly different" in your answer. Note: no credit will be given for ANY text outside the box or hard to read answers (d, 2 pts) State your biological conclusion in the box below. Do not use technical statistical terms; write this in plain language-are the loci close to one another or not?

Hello, please show work :) . I want to double check my work and answers . thanks

Answer 1

Con sidc'e the foiboo ing situatiOh ' at the fist locus AA' homoz9otcs ose Blacl us is aJote 293 69 236 235 103 ToTOA.16 q26339 2 60 u61 221 12 3 63.9s hit ו, וי'43