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14. Saquinavir (trade name Invirase) is a protease inhibitor, used to treat HIV (human immunodefi...
5,55 Locate the stereogenic centers in telaprevir, a drug used to treat hepatitis C, and label each stereogenic cen...
5,55 Locate the stereogenic centers in telaprevir, a drug used to treat hepatitis C, and label each stereogenic center as R or S 0 EI telaprevir
Please help me with these two problems. I will rate the answers. 1. The HIV-1 protease,...
Please help me with these two problems. I will rate the
answers.
1. The HIV-1 protease, an important enzyme in the life cycle of the human immunodeficiency virus-1 (HIV-1), is a good drug target for the treatment of HIV and AIDS. A protein produced by the virus, p6*, is an HIV-1 protease inhibitor. The activity of the HIV-1 protease was measured in the presence and absence of p6* using an assay involving an artificial substrate, as shown below. NH Lys...
3. Consider the real world objects below exterior interior of human of human bod bod A...
3. Consider the real world objects below exterior interior of human of human bod bod A roll of ta A nail A screw Which are chiral, and which are achiral? It is easier to prove an object is achiral than to prove it's chiral. You can prove an object is achiral in two ways a. i. draw its mirror image, and show that the mirror image is superimposable on the original ii. find a plane of symmetry in the original...
Polymyxin B, sold under the brand name Poly-Rx among others, is an antibiotic used to treat...
Polymyxin B, sold under the brand name Poly-Rx among others, is an antibiotic used to treat meningitis, pneumonia, sepsis. and urinary tract infections. Its structure is shown below. How many stereogenic chiral carbon centers do we have in the structure of Polymyxin B? Select one: a. 13 O b. 15 O c.ll 0 d. 14 f10 9.8 h. 12
1. a. The large structure shown below has recently been studied by the pharmaceutical company Merck....
1. a. The large structure shown below has recently been studied by the pharmaceutical company Merck. Using the numbering system shown for this structure, write (R) or (S) over the numbered line for each stereogenic center. b. (-)-Menthol is shown as the most stable chair conformation. Write the (R) or (S) stereochemistry above the atom numbers. c. Isoleucine is one of the twenty common amino acids. All of the stereogenic centers are (S). Draw the hydrogens to show those stereocenters....
Since the 1980s, HIV (Human Immunodeficiency Virus) has been infecting humans around the world causing the...
Since the 1980s, HIV (Human Immunodeficiency Virus) has been infecting humans around the world causing the condition known as AIDS (Acquired Immune Deficiency Syndrome). HIV, like all viruses, needs to enter cells and use their machinery to reproduce and spread. During HIV infection, the virus enters specific cells of the immune system (T-cells) by "docking" onto cell surface proteins, including one called CCR5 Genetic analysis of individuals who are naturally immune (resistant) to HIV have revealed that resistance to HIV...
19-26 thanks! 19-29* PART 3: 2,3-BUTANEDIOL CH-CH(OH)-CH(OH)-CH, mirror images, not superimposable Build as many models of...
19-26 thanks!
19-29*
PART 3: 2,3-BUTANEDIOL CH-CH(OH)-CH(OH)-CH, mirror images, not superimposable Build as many models of 2,3-butanediol as you can. First, attach two carbons with a single bond. To each carbon add one carbon, one hydrogen, and one oxygen. To complete the structure, Ti the remaining hydrogen atoms. Remember, a model is not different if it is completely superimposable on one already constructed! 13. How many stereochemically different models are possible for 2,3-butanediol? 14. What characteristic does one of these...
7. The IUPAC name for the followe d in the OH controls a) 3-chloro-2-methylcyclohexanol 5-chloro-2-methylcyclohexanol 2-methyl-3-chlorocyclohexanol...
7. The IUPAC name for the followe d in the OH controls a) 3-chloro-2-methylcyclohexanol 5-chloro-2-methylcyclohexanol 2-methyl-3-chlorocyclohexanol d) 2-methyl-5 chlorocyclohexanol e) 1-chloro-4-methylcyclohexanol Which of the following cannot be an electrophile? a) H b) CH2-CH; c) 'NO ) BF; d) Fee ased on the following enery diagram, which compound is formed slowly Reaction ) B from A c) Cfrom B d) from C a) A from B b 10. Which of the following has the highest priority? -0-H -CH=CHCH -CH=NCH -SC-CH; 11....
Please complete for Tuesday, we will go through the questions and mark them in class. pg 156 - 4.23,...
Please complete for Tuesday, we will go through the questions and mark them in class. pg 156 - 4.23, 4.24, 4.26 pg 170 - 4.29, 4.31, pg 171-4.36 pg 175 - 4.59 pg 176- 4.74, 4.75, 4.80 pg 177-4.81, 4.82 pg 188- 5.1, 5.4, 5.5, 5.6, 5.11 - Using Table 5.1 pg 198-5.22, 5.25 pg 203 - 5.29 pg 206 - 5.37 pg 209 - 5.39 pg 2.14 5.61 pg 235-6.11, 6.14, 6.16 156 CHAPTER 4 Introduction to Organic Compounds...
DATE: NURS 208A NAME: 1. The function of ribosomes is to: 6. Inb Digest foreign bacteria...
DATE: NURS 208A NAME: 1. The function of ribosomes is to: 6. Inb Digest foreign bacteria and toxic substances Produces energy from glucose y Aid in cell division Synthesize proteins Which of the following statement is false about the cell membrane? 2. Cell membrane is composed of phospholipid layer The cell membrane prefers large molecules to pass through freely Cell membrane is a semipermeable boundary which determines what can enter and ex the cell The exterior surface is hydrophilic phosphate...
5,55 Locate the stereogenic centers in telaprevir, a drug used to treat hepatitis C, and label each stereogenic center as R or S 0 EI telaprevir
Please help me with these two problems. I will rate the
answers.
1. The HIV-1 protease, an important enzyme in the life cycle of the human immunodeficiency virus-1 (HIV-1), is a good drug target for the treatment of HIV and AIDS. A protein produced by the virus, p6*, is an HIV-1 protease inhibitor. The activity of the HIV-1 protease was measured in the presence and absence of p6* using an assay involving an artificial substrate, as shown below. NH Lys...
3. Consider the real world objects below exterior interior of human of human bod bod A roll of ta A nail A screw Which are chiral, and which are achiral? It is easier to prove an object is achiral than to prove it's chiral. You can prove an object is achiral in two ways a. i. draw its mirror image, and show that the mirror image is superimposable on the original ii. find a plane of symmetry in the original...
Polymyxin B, sold under the brand name Poly-Rx among others, is an antibiotic used to treat meningitis, pneumonia, sepsis. and urinary tract infections. Its structure is shown below. How many stereogenic chiral carbon centers do we have in the structure of Polymyxin B? Select one: a. 13 O b. 15 O c.ll 0 d. 14 f10 9.8 h. 12
1. a. The large structure shown below has recently been studied by the pharmaceutical company Merck. Using the numbering system shown for this structure, write (R) or (S) over the numbered line for each stereogenic center. b. (-)-Menthol is shown as the most stable chair conformation. Write the (R) or (S) stereochemistry above the atom numbers. c. Isoleucine is one of the twenty common amino acids. All of the stereogenic centers are (S). Draw the hydrogens to show those stereocenters....
Since the 1980s, HIV (Human Immunodeficiency Virus) has been infecting humans around the world causing the condition known as AIDS (Acquired Immune Deficiency Syndrome). HIV, like all viruses, needs to enter cells and use their machinery to reproduce and spread. During HIV infection, the virus enters specific cells of the immune system (T-cells) by "docking" onto cell surface proteins, including one called CCR5 Genetic analysis of individuals who are naturally immune (resistant) to HIV have revealed that resistance to HIV...
19-26 thanks!
19-29*
PART 3: 2,3-BUTANEDIOL CH-CH(OH)-CH(OH)-CH, mirror images, not superimposable Build as many models of 2,3-butanediol as you can. First, attach two carbons with a single bond. To each carbon add one carbon, one hydrogen, and one oxygen. To complete the structure, Ti the remaining hydrogen atoms. Remember, a model is not different if it is completely superimposable on one already constructed! 13. How many stereochemically different models are possible for 2,3-butanediol? 14. What characteristic does one of these...
7. The IUPAC name for the followe d in the OH controls a) 3-chloro-2-methylcyclohexanol 5-chloro-2-methylcyclohexanol 2-methyl-3-chlorocyclohexanol d) 2-methyl-5 chlorocyclohexanol e) 1-chloro-4-methylcyclohexanol Which of the following cannot be an electrophile? a) H b) CH2-CH; c) 'NO ) BF; d) Fee ased on the following enery diagram, which compound is formed slowly Reaction ) B from A c) Cfrom B d) from C a) A from B b 10. Which of the following has the highest priority? -0-H -CH=CHCH -CH=NCH -SC-CH; 11....
Please complete for Tuesday, we will go through the questions and mark them in class. pg 156 - 4.23, 4.24, 4.26 pg 170 - 4.29, 4.31, pg 171-4.36 pg 175 - 4.59 pg 176- 4.74, 4.75, 4.80 pg 177-4.81, 4.82 pg 188- 5.1, 5.4, 5.5, 5.6, 5.11 - Using Table 5.1 pg 198-5.22, 5.25 pg 203 - 5.29 pg 206 - 5.37 pg 209 - 5.39 pg 2.14 5.61 pg 235-6.11, 6.14, 6.16 156 CHAPTER 4 Introduction to Organic Compounds...
DATE: NURS 208A NAME: 1. The function of ribosomes is to: 6. Inb Digest foreign bacteria and toxic substances Produces energy from glucose y Aid in cell division Synthesize proteins Which of the following statement is false about the cell membrane? 2. Cell membrane is composed of phospholipid layer The cell membrane prefers large molecules to pass through freely Cell membrane is a semipermeable boundary which determines what can enter and ex the cell The exterior surface is hydrophilic phosphate...
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