4)Draw stepwise mechanism that will explain the products of the following reaction. 5)draw the rate law and the transit...
(a) Draw a stepwise, detailed mechanism for the following reaction. Used curved arrows to show the movement of electrons. Br CN NaCN DMF NaBr (b) Assign the configuration (Ror S) of the chiral centre in the substrate and product (c) List the bonds broken and formed in this reaction (d) Assume that this is an endothermic reaction. Draw an energy diagram for this reaction. Label the axes, reactants, products, E, and AH. Draw the structure for both transition states.
Question 1 a) Draw the mechanism for the following E2 reaction. Use a chair conformation to illustrate the correct geometry between the leaving group and the hydrogen being eliminated. Tso NaOCHz + CH,OH + NaOTs b) Draw the 5-coordinate transition state that occurs during the Sn2 reaction below. NaCN DMSO c) Draw a complete mechanism for the transformation below. Be sure to include all curved arrows, intermediates, and by-products. H2SO4 (aq) OH OH الميم
4. Predict the products of the following reactions & indicate whether they are most likely to go through an SN2, SN1, E1, or E2 mechanism. NaCN DMSO NaOH CH3OH heat Only one product is formed in the following E2 elimination reaction. Draw an arrow-pushing mechanism for the reaction and provide the correct product structure. Include a 3-D drawing (chair conformation) displaying proper stereochemistry of the transition state to explain formation of only the major product. CH3 •Br NaOCH3 ~"'CHS
4.Draw a stepwise detailed mechanism that illustrates how four organic products are formed in the following reaction: (20 pts.) H₂ CH₂ CH,OH CH H.C. H₂C Н.С. OCH, CH, 880.
1. Write the predicted product and the rate law for the following reaction: CH;CH CH CI + NaCN DMSO 2. In the following reaction, identify a) the leaving group, b) the nucleophile, c) the electrophilic carbon and d) the solvent CH CH Br + NaHS H30 CH CH SH + NaBr 3. Write out the reaction of (R)-2-bromopentane with sodium cyanide in DMSO, including the predicted major product: 4. Rank the following in decreasing order of leaving group ability (with...
Predict the product of the following substitution reaction and then draw a stepwise mechanism for the reaction: Part 1: OCH3 CH3OH view structure Part 2: Br- + CH3Br CH3CH2Br HBr view structure view structure Part 3: H-O CH view structure view structure Part 4 out of 4 CH -8-01 OCH3 finish structure ... 3 attempts left Check my work Next part
4. Propose a mechanism for the formation of the following products OH +OH Br 5. Draw the structure of product formed in the following reaction Cl C4HgS Na DMSO Cl Draw the mechanism leading to product formation.
3. Draw a stepwise, detailed mechanism for the acid-catalyzed hydration reaction in question 2 above. Use curved arrows to indicate the flow of electrons. (Note: use hydronium ion, H307, in your mechanism to indicate "acidic water"). (6 pts) 4. Draw a stepwise, detailed mechanism for the reaction below. Use curved arrows to indicate the flow of electrons. (Hint: think of this reaction as a combination of addition of HX (step 1) and hydration (step 2)]. In the second step, an...
7) Give the mechanism including the transition state. сн.ct çı SN2 НН 8) Give the mechanism. CH1 보 SN1 CHCH,CH-C CH. но H Br 9) Give the mechanism of the reaction shown below. CH CI E1 CH,OH 10) When 1-bromo-2,2-dimethylcyclopentane is heated in ethanol, one of the products which results is shown below. Provide a detailed, stepwise mechanism for the production of this compound, and give the name of the mechanism by which it is produced. CH3 CH3
20. Draw a stepwise arrow pushing mechanism for the following reaction: ROOR 21. a. HCE CH b. Devise a synthesis of the following molecules beginning with ethane as the starting material: OH C. d. 22. Beginning with cyclopentane, devise a synthesis of the following molecules: он a. OH он CN